tert-butyl 4-aMino-3,4-dihydroisoquinoline-2(1H)-carboxylate

Base Information

Chemical Name:tert-butyl 4-aMino-3,4-dihydroisoquinoline-2(1H)-carboxylate
CAS No.:1145753-88-3
Molecular Formula:C₁₄H₂₀N₂O₂
Molecular Weight:248.325
Hs Code.:
Mol file:1145753-88-3.mol

Synonyms:tert-butyl 4-aMino-3,4-dihydroisoquinoline-2(1H)-carboxylate;4-Amino-3,4-dihydro-2(1H)-isoquinolinecarboxylic acid tert-butyl ester

Suppliers and Price of tert-butyl 4-aMino-3,4-dihydroisoquinoline-2(1H)-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
tert-Butyl4-amino-3,4-dihydroisoquinoline-2(1H)-carboxylate 95+%
1g
$ 1330.00

Chemenu
tert-butyl4-amino-3,4-dihydroisoquinoline-2(1H)-carboxylate 95%
1g
$ 1253.00

American Custom Chemicals Corporation
TERT-BUTYL 4-AMINO-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE 95.00%
5MG
$ 498.15

Alichem
tert-Butyl4-amino-3,4-dihydroisoquinoline-2(1H)-carboxylate
1g
$ 1086.76

Total 10 raw suppliers

Chemical Property of tert-butyl 4-aMino-3,4-dihydroisoquinoline-2(1H)-carboxylate

Chemical Property:

PSA：55.56000
Density:1.118
LogP:3.07530
Storage Temp.:2-8°C(protect from light)

Purity/Quality:

97% ^*data from raw suppliers

tert-Butyl4-amino-3,4-dihydroisoquinoline-2(1H)-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of tert-butyl 4-aMino-3,4-dihydroisoquinoline-2(1H)-carboxylate

There total 15 articles about tert-butyl 4-aMino-3,4-dihydroisoquinoline-2(1H)-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: tert-butyl 4-(2,2,2-trifluoroacetamido)-3,4-dihydroisoquinoline-2(1H)-carboxylate

: 1145753-88-3
tert-butyl 4-amino-3,4-dihydro-1H-isoquinoline-2-carboxylate

Guidance literature:: With water; potassium carbonate; In methanol; at 20 - 50 ℃;
DOI:10.1021/acsmedchemlett.0c00331

Reference yield:

: tert-butyl (4E)-4-hydroxyimino-1,3-dihydroisoquinoline-2-carboxylate

: 1145753-88-3
tert-butyl 4-amino-3,4-dihydro-1H-isoquinoline-2-carboxylate

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In isopropyl alcohol; at 25 ℃; for 16h;

Reference yield:

: 1134327-89-1
tert-butyl 4-oxo-1,3-dihydroisoquinoline-2-carboxylate

: 1145753-88-3
tert-butyl 4-amino-3,4-dihydro-1H-isoquinoline-2-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: hydroxylamine hydrochloride; pyridine / methanol / 2 h / 70 °C

2: palladium 10% on activated carbon; hydrogen / isopropyl alcohol / 16 h / 25 °C

With pyridine; palladium 10% on activated carbon; hydroxylamine hydrochloride; hydrogen; In methanol; isopropyl alcohol;