1-(2-Methoxyphenyl)-2-oxopyrrolidine-3-carboxylic acid

Base Information

Chemical Name:1-(2-Methoxyphenyl)-2-oxopyrrolidine-3-carboxylic acid
CAS No.:618070-28-3
Molecular Formula:C12H13NO4
Molecular Weight:235.24
Hs Code.:2933790090
European Community (EC) Number:632-180-7
DSSTox Substance ID:DTXSID40402160
Mol file:618070-28-3.mol

Synonyms:1-(2-methoxyphenyl)-2-oxopyrrolidine-3-carboxylic acid;618070-28-3;SCHEMBL892661;1-(2-Methoxyphenyl)-2-oxopyrrolidine-3-carboxylicacid;DTXSID40402160;QMNGUAWXPGHDJO-UHFFFAOYSA-N;MFCD03932869;AKOS000169575;AKOS022203223;CS-0357675;1-(2-METHOXYPHENYL)-2-OXO-3-PYRROLIDINECARBOXYLIC ACID

Suppliers and Price of 1-(2-Methoxyphenyl)-2-oxopyrrolidine-3-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-(2-Methoxyphenyl)-2-oxopyrrolidine-3-carboxylicacid 95+%
5g
$ 771.00

American Custom Chemicals Corporation
1-(2-METHOXYPHENYL)-2-OXOPYRROLIDINE-3-CARBOXYLIC ACID 95.00%
5MG
$ 498.60

AK Scientific
1-(2-Methoxyphenyl)-2-oxopyrrolidine-3-carboxylicacid
1g
$ 360.00

Total 3 raw suppliers

Chemical Property of 1-(2-Methoxyphenyl)-2-oxopyrrolidine-3-carboxylic acid

Chemical Property:

Melting Point:129～130℃
PSA：66.84000
LogP:1.19770
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:235.08445790
Heavy Atom Count:17
Complexity:318

Purity/Quality:

97% ^*data from raw suppliers

1-(2-Methoxyphenyl)-2-oxopyrrolidine-3-carboxylicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=CC=C1N2CCC(C2=O)C(=O)O

Technology Process of 1-(2-Methoxyphenyl)-2-oxopyrrolidine-3-carboxylic acid

There total 2 articles about 1-(2-Methoxyphenyl)-2-oxopyrrolidine-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 618070-28-3
1-(2-methoxyphenyl)-2-oxopyrrolidine-3-carboxylic acid

Guidance literature:

Reference yield: 82.5%

: 5617-70-9
cycl-isopropylidene cyclopropane-1,1-dicarboxylate

: 90-04-0
2-methoxy-phenylamine

: 618070-28-3
1-(2-methoxyphenyl)-2-oxopyrrolidine-3-carboxylic acid

Guidance literature:: In N,N-dimethyl-formamide; at 30 - 35 ℃; for 12h;
DOI:10.1016/j.bioorg.2020.103970

Reference yield:

: 618070-28-3
1-(2-methoxyphenyl)-2-oxopyrrolidine-3-carboxylic acid

: ethyl 7-((4-(4-aminophenoxy)-6-methoxyquinolin-7-yl)oxy)heptanoate

: C₃₇H₄₁N₃O₈

Guidance literature:: With triethylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In dichloromethane; at 40 ℃;
DOI:10.1016/j.bioorg.2020.103970