(2,2,6,6-Tetramethylpiperidin-4-yl)acetic acid

Base Information

Chemical Name:(2,2,6,6-Tetramethylpiperidin-4-yl)acetic acid
CAS No.:34635-77-3
Molecular Formula:C₁₁H₂₁NO₂
Molecular Weight:199.293
Hs Code.:2933399090
DSSTox Substance ID:DTXSID40397704
ChEMBL ID:CHEMBL1906762
Mol file:34635-77-3.mol

Synonyms:34635-77-3;2-(2,2,6,6-tetramethylpiperidin-4-yl)acetic acid;(2,2,6,6-Tetramethylpiperidin-4-yl)acetic acid;(2,2,6,6-Tetramethyl-piperidin-4-yl)-acetic acid;2-(2,2,6,6-tetramethyl-4-piperidyl)acetic acid;SCHEMBL4016063;CHEMBL1906762;DTXSID40397704;STK680346;AKOS000301979;SB41920;CS-0279256;2,2,6,6-tetramethyl-4-carboxymethylpiperidine;EN300-783086;2-(2,2,6,6-tetramethylpiperidin-4-yl)aceticacid

Suppliers and Price of (2,2,6,6-Tetramethylpiperidin-4-yl)acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
(2,2,6,6-Tetramethyl-piperidin-4-yl)-acetic acid
1g
$ 378.00

Crysdot
2-(2,2,6,6-Tetramethylpiperidin-4-yl)aceticacid 95+%
5g
$ 874.00

American Custom Chemicals Corporation
(2,2,6,6-TETRAMETHYL-PIPERIDIN-4-YL)-ACETIC ACID 95.00%
500MG
$ 777.32

AK Scientific
(2,2,6,6-Tetramethyl-piperidin-4-yl)-aceticacid
1g
$ 560.00

Total 9 raw suppliers

Chemical Property of (2,2,6,6-Tetramethylpiperidin-4-yl)acetic acid

Chemical Property:

Vapor Pressure:0.000297mmHg at 25°C
Boiling Point:298.7°C at 760 mmHg
Flash Point:134.4°C
PSA：49.33000
Density:0.942g/cm³
LogP:2.34670
XLogP3:-1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:199.157228913
Heavy Atom Count:14
Complexity:217

Purity/Quality:

98%min ^*data from raw suppliers

(2,2,6,6-Tetramethyl-piperidin-4-yl)-acetic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(CC(CC(N1)(C)C)CC(=O)O)C

Technology Process of (2,2,6,6-Tetramethylpiperidin-4-yl)acetic acid

There total 2 articles about (2,2,6,6-Tetramethylpiperidin-4-yl)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 28310-37-4
methyl 2,2,6,6-tetramethylpiperidyl-4-acetate

: 34635-77-3
2-(2,2,6,6-tetramethylpiperidin-4-yl)acetic acid

Guidance literature:: With sodium hydroxide; In ethanol; for 1h; Heating;
DOI:10.1007/BF00954287

Reference yield:

: 34635-77-3
2-(2,2,6,6-tetramethylpiperidin-4-yl)acetic acid

Guidance literature:: entspr. Ethylacetat, HCl;

Reference yield:

: 34635-77-3
2-(2,2,6,6-tetramethylpiperidin-4-yl)acetic acid

: 1620515-63-0
2-(2-methoxy-4-(1H-pyrazol-1-yl)phenyl)-5-((2,2,6,6-tetramethylpiperidin-4-yl)methyl)-1,3,4-thiadiazole

Guidance literature:: Multi-step reaction with 3 steps

1: trichlorophosphate / 75 h / 20 - 78 °C / Inert atmosphere; Cooling with ice; Sonication

2: tert.-butylnitrite; copper(ll) bromide / acetonitrile / 36 h / 20 °C / Inert atmosphere

3: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / water; 1,4-dioxane / 1 h / 120 °C / Inert atmosphere; Sealed tube; Microwave irradiation

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; tert.-butylnitrite; sodium carbonate; copper(ll) bromide; trichlorophosphate; In 1,4-dioxane; water; acetonitrile;