Technology Process of 2,6-Dichloro-5-propylnicotinonitrile
There total 3 articles about 2,6-Dichloro-5-propylnicotinonitrile which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetramethlyammonium chloride; trichlorophosphate;
In
toluene;
at 200 ℃;
for 5h;
Autoclave;
DOI:10.1016/j.bmc.2011.03.021
- Guidance literature:
-
Multi-step reaction with 3 steps
1: sodium hydride / tetrahydrofuran; mineral oil / 20 °C
2: potassium hydroxide / ethanol / 18 h / Reflux
3: tetramethlyammonium chloride; trichlorophosphate / toluene / 5 h / 200 °C / Autoclave
With
tetramethlyammonium chloride; sodium hydride; potassium hydroxide; trichlorophosphate;
In
tetrahydrofuran; ethanol; toluene; mineral oil;
1: Claisen condensation / 2: Guareschi-Thorpe condensation;
DOI:10.1016/j.bmc.2011.03.021
- Guidance literature:
-
Multi-step reaction with 2 steps
1: potassium hydroxide / ethanol / 18 h / Reflux
2: tetramethlyammonium chloride; trichlorophosphate / toluene / 5 h / 200 °C / Autoclave
With
tetramethlyammonium chloride; potassium hydroxide; trichlorophosphate;
In
ethanol; toluene;
1: Guareschi-Thorpe condensation;
DOI:10.1016/j.bmc.2011.03.021
