2-(2-Ethoxy-3-methoxyphenyl)ethanamine

Base Information

• Chemical Name: 2-(2-Ethoxy-3-methoxyphenyl)ethanamine
• CAS No.: 709649-59-2
• Molecular Formula: C11H17NO2
• Molecular Weight: 195.261
• DSSTox Substance ID: DTXSID30405862
• Wikidata: Q82210586
• Mol file: 709649-59-2.mol

Synonyms:2-(2-ethoxy-3-methoxyphenyl)ethanamine;87790-87-2;SCHEMBL1254108;DTXSID30405862;ZAFQGFANJDACBB-UHFFFAOYSA-N;BBL020708;STK893398;AKOS001476972;(2-ethoxy-3-methoxy-benzyl)methylamine;2-(2-ethoxy-3-methoxyphenyl)-1-ethanamine

Chemical Property of 2-(2-Ethoxy-3-methoxyphenyl)ethanamine

Chemical Property:

• Vapor Pressure: 0.0107mmHg at 25°C
• Boiling Point: 262.7°C at 760 mmHg
• Flash Point: 107.7°C
• Density: 0.998g/cm³
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 195.125928785
• Heavy Atom Count: 14
• Complexity: 152

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC1=C(C=CC=C1OC)CCN

Technology Process of 2-(2-Ethoxy-3-methoxyphenyl)ethanamine

There total 1 articles about 2-(2-Ethoxy-3-methoxyphenyl)ethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

→ (2-ethoxy-3-methoxy-benzyl)-methyl-amine (709649-59-2)

Guidance literature:

Reference yield: 49.0%

(2-ethoxy-3-methoxy-benzyl)-methyl-amine (709649-59-2) + 3-(5-hydroxy-7-oxo-7,8-dihydro-[1,8]naphthyridin-3-yl)-acrylic acid → N-(2-ethoxy-3-methoxy-benzyl)-3-(5-hydroxy-7-oxo-7,8-dihydro-[1,8]naphthyridin-3-yl)-N-methyl-acrylamide

Guidance literature:

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; for 17h;

Reference yield: 46.0%

(2-ethoxy-3-methoxy-benzyl)-methyl-amine (709649-59-2) + (2E)-3-(6-amino-3-pyridinyl)-2-propenoic acid (167837-43-6) → (E)-3-(6-amino-pyridin-3-yl)-N-(2-ethoxy-3-methoxy-benzyl)-N-methyl-acrylamide hydrochloride (709652-67-5)

Guidance literature:

(2-ethoxy-3-methoxy-benzyl)-methyl-amine; (2E)-3-(6-amino-3-pyridinyl)-2-propenoic acid; With benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; N-ethyl-N,N-diisopropylamine; In DMF (N,N-dimethyl-formamide); water; for 18h;

With hydrogenchloride; In diethyl ether; dichloromethane;

Downstream raw materials:

(E)-3-(6-amino-pyridin-3-yl)-N-(2-ethoxy-3-methoxy-benzyl)-N-methyl-acrylamide hydrochloride