[O6-(DIMETHOXYTRITYL)HEXYL][6'-HYDROXYHEXYL]DISULFIDE

Base Information

• Chemical Name: [O6-(DIMETHOXYTRITYL)HEXYL][6'-HYDROXYHEXYL]DISULFIDE
• CAS No.: 148254-18-6
• Molecular Formula: C33H44O4S2
• Molecular Weight: 568.83
• Mol file: 148254-18-6.mol

Synonyms:[O6-(DIMETHOXYTRITYL)HEXYL][6'-HYDROXYHEXYL]DISULFIDE;[O6-(DMT)-HEXYL][6'-HYDROXYHEXYL]DISULFIDE

Chemical Property of [O6-(DIMETHOXYTRITYL)HEXYL][6'-HYDROXYHEXYL]DISULFIDE

Chemical Property:

• PSA: 98.52000
• LogP: 8.50680

Purity/Quality:

98%min ^*data from raw suppliers

[O6-(DIMETHOXYTRITYL)HEXYL][6'-HYDROXYHEXYL]DISULFIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of [O6-(DIMETHOXYTRITYL)HEXYL][6'-HYDROXYHEXYL]DISULFIDE

There total 3 articles about [O6-(DIMETHOXYTRITYL)HEXYL][6'-HYDROXYHEXYL]DISULFIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

4,4'-dimethoxytrityl chloride (40615-36-9) + 6,6’-disulfanediylbis(hexan-1-ol) (80901-86-6) → 6-({6-[bis(4-methoxyphenyl)phenylmethoxy]hexyl}disulfanyl)hexan-1-ol (148254-18-6)

Guidance literature:

With pyridine; at 20 ℃;

DOI:10.1039/b813289e

Reference yield:

4,4'-dimethoxytrityl chloride (40615-36-9) → 6-({6-[bis(4-methoxyphenyl)phenylmethoxy]hexyl}disulfanyl)hexan-1-ol (148254-18-6)

Guidance literature:

With pyridine; In ethyl acetate;

Reference yield:

1,6-hexanediol (629-11-8) + 4,4'-dimethoxytrityl chloride (40615-36-9) → 6-({6-[bis(4-methoxyphenyl)phenylmethoxy]hexyl}disulfanyl)hexan-1-ol (148254-18-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: triethylamine / tetrahydrofuran / 20 °C

1.2: 0 - 20 °C / Cooling with ice

1.3: 75 °C

2.1: triethylamine / dichloromethane / 0.5 h / 20 °C

With triethylamine; In tetrahydrofuran; dichloromethane;

upstream raw materials:

4,4'-dimethoxytrityl chloride

6,6’-disulfanediylbis(hexan-1-ol)

1,6-hexanediol

Downstream raw materials:

C₃₇H₄₈O₇S₂

C₄₂H₆₁N₂O₅PS₂