4-ACETOXY-3-IODOBENZOIC ACID

Base Information

• Chemical Name: 4-ACETOXY-3-IODOBENZOIC ACID
• CAS No.: 190067-59-5
• Molecular Formula: C9H7IO4
• Molecular Weight: 306.057
• Mol file: 190067-59-5.mol

Synonyms:4-ACETOXY-3-IODOBENZOIC ACID;4-(acetyloxy)-3-iodoBenzoic acid

Chemical Property of 4-ACETOXY-3-IODOBENZOIC ACID

Chemical Property:

• Vapor Pressure: 6.24E-07mmHg at 25°C
• Boiling Point: 394.5°C at 760 mmHg
• Flash Point: 192.4°C
• PSA: 63.60000
• Density: 1.893g/cm³
• LogP: 1.91470
• Storage Temp.: 2-8°C

Purity/Quality:

95% ^*data from raw suppliers

4-Acetoxy-3-iodobenzoicacid 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-ACETOXY-3-IODOBENZOIC ACID

There total 4 articles about 4-ACETOXY-3-IODOBENZOIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.4%

4-acetyloxy-benzoic acid (2345-34-8) → 4-acetoxy-3-iodo-benzoic acid (190067-59-5)

Guidance literature:

With sodium periodate; sulfuric acid; iodine; acetic anhydride; acetic acid; at 0 - 45 ℃;

Reference yield:

methyl 4-hydroxylbenzoate (99-76-3,156291-94-0) → 4-acetoxy-3-iodo-benzoic acid (190067-59-5)

Guidance literature:

With potassium iodide; sodium methylate; sodium; sodium thiosulfate; In methanol;

Reference yield:

4-hydroxy-benzoic acid (99-96-7) → 4-acetoxy-3-iodo-benzoic acid (190067-59-5)

Guidance literature:

Multi-step reaction with 2 steps

1: mercury oxide; alcohol; iodine

With ethanol; iodine; mercury(II) oxide;

DOI:10.1557/JMR.2000.0081

upstream raw materials:

4-hydroxy-benzoic acid

3-amino-4-hydroxybenzoic acid

methyl 4-hydroxylbenzoate

4-acetyloxy-benzoic acid

Downstream raw materials:

2-tert-butylbenzofuran-5-carboxylic acid

(4-hydroxy-3-iodophenyl)(2-(4-methoxyphenyl)-5-methylbenzofuran-3-yl)methanone

2-phenyl-benzofuran-5-carboxylic acid

Refernces

• 1、 -. "Combinatorial solid phase synthesis of a library of benzofuran derivatives". . . Retrieved 2008/06/13.