1-(piperidin-1-yl)-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)ethanone

Base Information

Chemical Name:1-(piperidin-1-yl)-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)ethanone
CAS No.:1203671-47-9
Molecular Formula:C16H26BN3O3
Molecular Weight:319.212
Hs Code.:2934999090
DSSTox Substance ID:DTXSID50694978
Wikidata:Q82623940
Mol file:1203671-47-9.mol

Synonyms:1203671-47-9;1-(piperidin-1-yl)-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)ethanone;1-piperidin-1-yl-2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazol-1-yl]ethanone;1-PIPERIDIN-1-YL-2-[4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRAZOL-1-YL]-ETHANONE;(1-(2-OXO-2-(PIPERIDIN-1-YL)ETHYL)-1H-PYRAZOL-4-YL)BORONIC ACID PINACOL ESTER;1-(Piperidin-1-yl)-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)ethan-1-one;1-(Piperidin-1-yl)-2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]ethan-1-one;SCHEMBL992468;DTXSID50694978;MMKFAZFVNXUHSI-UHFFFAOYSA-N;MFCD17926461;AS-38273;CS-0171673;FT-0711918;A910260;A1-13166

Suppliers and Price of 1-(piperidin-1-yl)-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)ethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
1-Piperidin-1-yl-2-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyrazol-1-yl]-ethanone 95%
1g
$ 1073.00

AstaTech
(1-(2-OXO-2-(PIPERIDIN-1-YL)ETHYL)-1H-PYRAZOL-4-YL)BORONICACIDPINACOLESTER 97%
1 / G
$ 585.00

AstaTech
(1-(2-OXO-2-(PIPERIDIN-1-YL)ETHYL)-1H-PYRAZOL-4-YL)BORONICACIDPINACOLESTER 97%
0.25 / G
$ 209.00

AstaTech
(1-(2-OXO-2-(PIPERIDIN-1-YL)ETHYL)-1H-PYRAZOL-4-YL)BORONICACIDPINACOLESTER 97%
0.1 / G
$ 136.00

Alichem
1-(Piperidin-1-yl)-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)ethanone
1g
$ 676.20

AK Scientific
1-(Piperidin-1-yl)-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)ethanone
1g
$ 1006.00

A1 Biochem Labs
1-Piperidin-1-yl-2-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyrazol-1-yl]-ethanone 95%
2.5 g
$ 850.00

Total 6 raw suppliers

Chemical Property of 1-(piperidin-1-yl)-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)ethanone

Chemical Property:

Boiling Point:487.1±25.0 °C(Predicted)
PKA:1.70±0.10(Predicted)
PSA：56.59000
Density:1.16±0.1 g/cm3(Predicted)
LogP:1.13270
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:319.2067219
Heavy Atom Count:23
Complexity:436

Purity/Quality:

97% ^*data from raw suppliers

1-Piperidin-1-yl-2-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyrazol-1-yl]-ethanone 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:B1(OC(C(O1)(C)C)(C)C)C2=CN(N=C2)CC(=O)N3CCCCC3

Technology Process of 1-(piperidin-1-yl)-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)ethanone

There total 1 articles about 1-(piperidin-1-yl)-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 1796-25-4
1-(2-bromoacetyl)piperidine

: 269410-08-4
pyrazole-4-boronic acid pinacol ester

: 1203671-47-9
1-(piperidin-1-yl)-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)ethanone

Guidance literature:: pyrazole-4-boronic acid pinacol ester; With caesium carbonate; In acetonitrile; at 20 ℃; for 0.5h;

1-(2-bromoacetyl)piperidine; In acetonitrile; at 20 ℃; for 18h;

Reference yield: 41.0%

: 1203671-47-9
1-(piperidin-1-yl)-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)ethanone

: 6-(3-amino-6-bromopyrazin-2-yl)-2-(2,6-dichloro-3,5-dimethoxyphenyl)pyridazin-3(2H)-one

: 6-(3-amino-6-(1-(2-oxo-2-(piperidin-1-yl)ethyl)-1H-pyrazol-4-yl)pyrazin-2-yl)-2-(2,6-dichloro-3,5-dimethoxyphenyl)pyridazin-3(2H)-one

Guidance literature:: 1-(piperidin-1-yl)-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)ethanone; 6-(3-amino-6-bromopyrazin-2-yl)-2-(2,6-dichloro-3,5-dimethoxyphenyl)pyridazin-3(2H)-one; With sodium carbonate; In 1,4-dioxane; for 0.0833333h; Inert atmosphere;

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; at 100 ℃; for 2.5h; Inert atmosphere;