1,3-Dioxolane-4-ethanol,alpha,4-diethyl-2,2-dimethyl-,(4R)-(9CI)

Base Information

Chemical Name:1,3-Dioxolane-4-ethanol,alpha,4-diethyl-2,2-dimethyl-,(4R)-(9CI)
CAS No.:460076-91-9
Molecular Formula:C₁₁H₂₂O₃
Molecular Weight:202.294
Hs Code.:
Mol file:460076-91-9.mol

Synonyms:1,3-Dioxolane-4-ethanol,alpha,4-diethyl-2,2-dimethyl-,(4R)-(9CI)

Suppliers and Price of 1,3-Dioxolane-4-ethanol,alpha,4-diethyl-2,2-dimethyl-,(4R)-(9CI)

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1,3-Dioxolane-4-ethanol,alpha,4-diethyl-2,2-dimethyl-,(4R)-(9CI)

Chemical Property:

PSA：38.69000
LogP:2.07910

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1,3-Dioxolane-4-ethanol,alpha,4-diethyl-2,2-dimethyl-,(4R)-(9CI)

There total 5 articles about 1,3-Dioxolane-4-ethanol,alpha,4-diethyl-2,2-dimethyl-,(4R)-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 925-90-6
ethylmagnesium bromide

: 106268-09-1
(3R)-3-hydroxy-3-(hydroxymethyl)-3,3'-O-isopropylidenepentanal

: 460076-91-9
(4R)-1-(4-ethyl-2,2-dimethyl-1,3-dioxolan-4-yl)butan-2-ol

Guidance literature:: ethylmagnesium bromide; (3R)-3-hydroxy-3-(hydroxymethyl)-3,3'-O-isopropylidenepentanal; In tetrahydrofuran; at -78 - 20 ℃;

With water; ammonium chloride; In tetrahydrofuran;
DOI:10.1021/jo101224w

Reference yield:

: 460076-88-4
1-(3-ethyl-but-3-enyloxy)-4-methoxy-benzene

: 460076-91-9
(4R)-1-(4-ethyl-2,2-dimethyl-1,3-dioxolan-4-yl)butan-2-ol

Guidance literature:: Multi-step reaction with 5 steps

1: AD mix-β; H2O / 2-methyl-propan-2-ol

2: PTSA

3: CAN

4: TPAP; NMO

With N-methyl-2-indolinone; tetrapropylammonium perruthennate; ammonium cerium(IV) nitrate; water; toluene-4-sulfonic acid; 1,4-bis(9-O-dihydroquinidine)phthalazine; In tert-butyl alcohol;
DOI:10.1021/ja026728s

Reference yield:

: 460076-90-8
(R)-2-(4-ethyl-2,2-dimethyl-1,3-dioxolan-4-yl)ethanol

: 460076-91-9
(4R)-1-(4-ethyl-2,2-dimethyl-1,3-dioxolan-4-yl)butan-2-ol

Guidance literature:: Multi-step reaction with 2 steps

1: TPAP; NMO

With N-methyl-2-indolinone; tetrapropylammonium perruthennate;
DOI:10.1021/ja026728s