4-(4-(Methylsulfonyl)piperazin-1-yl)phenol

Base Information

Chemical Name:4-(4-(Methylsulfonyl)piperazin-1-yl)phenol
CAS No.:67915-03-1
Molecular Formula:C11H16N2O3S
Molecular Weight:256.326
Hs Code.:2933599090
DSSTox Substance ID:DTXSID30348689
Wikidata:Q82123656

Synonyms:4-(4-(methylsulfonyl)piperazin-1-yl)phenol;67915-03-1;4-(4-methylsulfonylpiperazin-1-yl)phenol;4-(4-methanesulfonylpiperazin-1-yl)phenol;4-[4-(methylsulfonyl)piperazin-1-yl]phenol;SCHEMBL2453453;DTXSID30348689;MFCD16090027;AKOS005073815;SS-3912;FT-0722395;1-(4-hydroxyphenyl)-4-(methylsulfonyl)piperazine;1-(4-hydroxyphenyl)-4-(methylsulfonyl)-piperazine;piperazine, 1-(4-hydroxyphenyl)-4-(methylsulfonyl)-

Suppliers and Price of 4-(4-(Methylsulfonyl)piperazin-1-yl)phenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
4-(4-(Methylsulfonyl)piperazin-1-yl)phenol >95%
1g
$ 454.00

Matrix Scientific
4-(4-(Methylsulfonyl)piperazin-1-yl)phenol >95%
500mg
$ 362.00

AK Scientific
4-(4-(Methylsulfonyl)piperazin-1-yl)phenol
1g
$ 662.00

Total 2 raw suppliers

Chemical Property of 4-(4-(Methylsulfonyl)piperazin-1-yl)phenol

Chemical Property:

PSA：69.23000
LogP:1.55750
XLogP3:0.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:256.08816355
Heavy Atom Count:17
Complexity:336

Purity/Quality:

98%min ^*data from raw suppliers

4-(4-(Methylsulfonyl)piperazin-1-yl)phenol >95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CS(=O)(=O)N1CCN(CC1)C2=CC=C(C=C2)O

Technology Process of 4-(4-(Methylsulfonyl)piperazin-1-yl)phenol

There total 5 articles about 4-(4-(Methylsulfonyl)piperazin-1-yl)phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 133357-71-8
methanesulfonic acid 4-(4-methanesulfonylpiperazin-1-yl)phenyl ester

: 67915-03-1
1-(4-Hydroxyphenyl)-4-(methanesulfonyl)piperazine

Guidance literature:: With sodium hydroxide; for 12h; Yield given; Heating;
DOI:10.1002/jhet.5570270739

Reference yield:

: 38869-37-3
1-(4-hydroxy-phenyl)-piperazine dihydrobromide

: 67915-03-1
1-(4-Hydroxyphenyl)-4-(methanesulfonyl)piperazine

Guidance literature:: Multi-step reaction with 2 steps

1: 97 percent / pyridine / 0.5 h

2: 1N aq. NaOH / 12 h / Heating

With sodium hydroxide; In pyridine;
DOI:10.1002/jhet.5570270739

Reference yield:

: 38869-47-5,70849-64-8
4-(p-methoxyphenyl)piperazine dihydrochloride

: 67915-03-1
1-(4-Hydroxyphenyl)-4-(methanesulfonyl)piperazine

Guidance literature:: Multi-step reaction with 3 steps

1: 88 percent / 48percent HBr / 4 h / 140 °C

2: 97 percent / pyridine / 0.5 h

3: 1N aq. NaOH / 12 h / Heating

With sodium hydroxide; hydrogen bromide; In pyridine;
DOI:10.1002/jhet.5570270739