Technology Process of 2-Amino-5-nitro-1-naphthalenesulfonic acid
There total 1 articles about 2-Amino-5-nitro-1-naphthalenesulfonic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
2-aminonaphthalenesulfonic acid;
With
sulfuric acid;
at -10 - -5 ℃;
With
potassium nitrate;
at -15 ℃;
for 0.666667h;
Overall yield = 95 %; Overall yield = 9.65 g;
DOI:10.1021/acs.jmedchem.5b01517
- Guidance literature:
-
Multi-step reaction with 3 steps
1: sulfuric acid / water / 0.67 h / Reflux
2: sulfuric acid; acetic acid; sodium nitrite / 0.25 h / 15 - 20 °C
3: copper(l) chloride; sulfuric acid; acetic acid; hydrogenchloride / 20 °C
With
hydrogenchloride; sulfuric acid; acetic acid; copper(l) chloride; sodium nitrite;
In
water;
3: |Sandmeyer Reaction;
DOI:10.1021/acs.jmedchem.5b01517
- Guidance literature:
-
Multi-step reaction with 4 steps
1: sulfuric acid / water / 0.67 h / Reflux
2: sulfuric acid; acetic acid; sodium nitrite / 0.25 h / 15 - 20 °C
3: copper(l) chloride; sulfuric acid; acetic acid; hydrogenchloride / 20 °C
4: tin(II) chloride dihdyrate / ethanol / 20 °C
With
hydrogenchloride; tin(II) chloride dihdyrate; sulfuric acid; acetic acid; copper(l) chloride; sodium nitrite;
In
ethanol; water;
3: |Sandmeyer Reaction;
DOI:10.1021/acs.jmedchem.5b01517