2-(1H-imidazol-1-yl)-5-(trifluoromethyl)aniline

Base Information

Chemical Name:2-(1H-imidazol-1-yl)-5-(trifluoromethyl)aniline
CAS No.:380389-67-3
Molecular Formula:C₁₀H₈F₃N₃
Molecular Weight:227.189
Hs Code.:
DSSTox Substance ID:DTXSID60406564
Wikidata:Q82211588
Mol file:380389-67-3.mol

Synonyms:2-(1H-imidazol-1-yl)-5-(trifluoromethyl)aniline;380389-67-3;2-imidazol-1-yl-5-(trifluoromethyl)aniline;[2-(1H-Imidazol-1-yl)-5-(trifluoromethyl)phenyl]amine hydrochloride;HMS1736G06;SCHEMBL2935531;DTXSID60406564;AKOS000128157;CS-0268754;EN300-57974;SR-01000072447;SR-01000072447-1

Suppliers and Price of 2-(1H-imidazol-1-yl)-5-(trifluoromethyl)aniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(1H-Imidazol-1-yl)-5-(trifluoromethyl)aniline
50mg
$ 60.00

Matrix Scientific
2-(1H-Imidazol-1-yl)-5-(trifluoromethyl)aniline
500mg
$ 252.00

Crysdot
2-(1H-Imidazol-1-yl)-5-(trifluoromethyl)aniline 95+%
5g
$ 527.00

Chemenu
2-(1H-Imidazol-1-yl)-5-(trifluoromethyl)aniline 95%
5g
$ 497.00

ChemBridge Corporation
2-(1H-imidazol-1-yl)-5-(trifluoromethyl)aniline 95%
250 mg
$ 64.00

American Custom Chemicals Corporation
2-(1H-IMIDAZOL-1-YL)-5-(TRIFLUOROMETHYL)ANILINE 95.00%
5G
$ 1155.00

American Custom Chemicals Corporation
2-(1H-IMIDAZOL-1-YL)-5-(TRIFLUOROMETHYL)ANILINE 95.00%
1G
$ 693.00

American Custom Chemicals Corporation
2-(1H-IMIDAZOL-1-YL)-5-(TRIFLUOROMETHYL)ANILINE 95.00%
0.5G
$ 638.00

AK Scientific
2-(1H-Imidazol-1-yl)-5-(trifluoromethyl)aniline
500mg
$ 390.00

Total 9 raw suppliers

Chemical Property of 2-(1H-imidazol-1-yl)-5-(trifluoromethyl)aniline

Chemical Property:

Vapor Pressure:0.000114mmHg at 25°C
Boiling Point:336.2°C at 760 mmHg
Flash Point:157.1°C
PSA：43.84000
Density:1.39g/cm³
LogP:3.05450
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:227.06703175
Heavy Atom Count:16
Complexity:244

Purity/Quality:

98%min ^*data from raw suppliers

2-(1H-Imidazol-1-yl)-5-(trifluoromethyl)aniline ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1C(F)(F)F)N)N2C=CN=C2

Technology Process of 2-(1H-imidazol-1-yl)-5-(trifluoromethyl)aniline

There total 3 articles about 2-(1H-imidazol-1-yl)-5-(trifluoromethyl)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 367-86-2
1-fluoro-2-nitro-4-trifluoromethyl-benzene

: 380389-67-3
2-(1H-imidazol-1-yl)-5-(trifluoromethyl)aniline

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydroxide / dimethyl sulfoxide / 19 h / 20 °C

2: palladium 10% on activated carbon / ethanol / 20 °C / 3000.3 Torr / Inert atmosphere

With palladium 10% on activated carbon; sodium hydroxide; In ethanol; dimethyl sulfoxide;
DOI:10.1039/c6cc09160a

Reference yield:

: 121-17-5
2-chloro-3-nitro-5-trifluoromethylbenzene

: 380389-67-3
2-(1H-imidazol-1-yl)-5-(trifluoromethyl)aniline

Guidance literature:: Multi-step reaction with 2 steps

1: 75 percent / K₂CO₃ / dimethylformamide / 1.5 h / 100 - 110 °C

2: 63 percent / Fe powder; HOAc / propan-2-ol / 1.5 h / Heating

With iron; potassium carbonate; acetic acid; In N,N-dimethyl-formamide; isopropyl alcohol;
DOI:10.1002/hc.10000