ent-14,15-Dir-13-oxolabda-8(17),11-dien-18-oic acid

Base Information

Chemical Name:ent-14,15-Dir-13-oxolabda-8(17),11-dien-18-oic acid
CAS No.:875585-30-1
Molecular Formula:C₁₈H₂₆O₃
Molecular Weight:290.403
Hs Code.:

Synonyms:ent-14,15-Dir-13-oxolabda-8(17),11-dien-18-oic acid;ent-14,15-Dinor-13-oxolabda-8(17),11-dien-18-oic acid

Suppliers and Price of ent-14,15-Dir-13-oxolabda-8(17),11-dien-18-oic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
ent-14,15-Dinor-13-oxolabda-8(17),11-dien-18-oicacid 95+%
5mg
$ 990.00

Arctom
ent-14,15-Dinor-13-oxolabda-8(17),11-dien-18-oicacid ≥98%
5mg
$ 653.00

Total 9 raw suppliers

Chemical Property of ent-14,15-Dir-13-oxolabda-8(17),11-dien-18-oic acid

Chemical Property:

PSA：54.37000
LogP:3.99510

Purity/Quality:

98%min ^*data from raw suppliers

ent-14,15-Dinor-13-oxolabda-8(17),11-dien-18-oicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of ent-14,15-Dir-13-oxolabda-8(17),11-dien-18-oic acid

There total 7 articles about ent-14,15-Dir-13-oxolabda-8(17),11-dien-18-oic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 329042-22-0
13-hydroxy-15,16-dinorlabda-8⁽¹⁷⁾,11E-dien-19-oic acid

: 875585-30-1
14,15-bisnor-13-oxo-8(17),11(E)-labdadien-19-oic acid

Guidance literature:: With dipyridinium dichromate; In N,N-dimethyl-formamide; at 20 ℃; for 7h;
DOI:10.1248/cpb.54.1333

Reference yield:

: 39668-54-7
(1S,4aR,5S,8aR)-methyl 1,4a-dimethyl-6-methylene-5-(2-oxoethyl)decahydronaphthalene-1-carboxylate

: 875585-30-1
14,15-bisnor-13-oxo-8(17),11(E)-labdadien-19-oic acid

Guidance literature:: Multi-step reaction with 7 steps

1.1: KO-tBu / diethyl ether / 0.5 h / 20 °C

1.2: 94 percent / diethyl ether / 7 h / 20 °C

2.1: 61 percent / PPTS / acetone / 3 h / 20 °C

3.1: KO-tBu / tetrahydrofuran / 5 h / -78 °C

4.1: 18.6 mg / aq. H₂O₂ / CH₂Cl₂ / 0.33 h / 20 °C

5.1: 97 percent / tetrahydrofuran / 0.25 h / 0 °C

6.1: 100 percent / HMPA; 1-dodecanethiol; n-BuLi / hexane / 2.5 h / 20 °C

7.1: 94 percent / PDC; Celite(R) / dimethylformamide / 7 h / 20 °C

With N,N,N,N,N,N-hexamethylphosphoric triamide; dipyridinium dichromate; n-butyllithium; Celite; potassium tert-butylate; dihydrogen peroxide; pyridinium p-toluenesulfonate; 1-dodecylthiol; In tetrahydrofuran; diethyl ether; hexane; dichloromethane; N,N-dimethyl-formamide; acetone; 1.2: Wittig reaction;
DOI:10.1248/cpb.50.1625

Reference yield:

: 501004-56-4
methyl 13-hydroxy-15,16-dinorlabda-8⁽¹⁷⁾,11E-dien-19-oate

: 875585-30-1
14,15-bisnor-13-oxo-8(17),11(E)-labdadien-19-oic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 100 percent / HMPA; 1-dodecanethiol; n-BuLi / hexane / 2.5 h / 20 °C

2: 94 percent / PDC; Celite(R) / dimethylformamide / 7 h / 20 °C

With N,N,N,N,N,N-hexamethylphosphoric triamide; dipyridinium dichromate; n-butyllithium; Celite; 1-dodecylthiol; In hexane; N,N-dimethyl-formamide;
DOI:10.1248/cpb.50.1625