RARECHEM AL BI 1384

Base Information

• Chemical Name: RARECHEM AL BI 1384
• CAS No.: 157372-95-7
• Molecular Formula: C10H8F2O3
• Molecular Weight: 214.169
• Mol file: 157372-95-7.mol

Synonyms:RARECHEM AL BI 1384;ETHYL 2,4-DIFLUOROBENZOYLFORMATE

Chemical Property of RARECHEM AL BI 1384

Chemical Property:

• Vapor Pressure: 0.0047mmHg at 25°C
• Boiling Point: 276.8°C at 760 mmHg
• Flash Point: 117.5°C
• PSA: 43.37000
• Density: 1.291g/cm³
• LogP: 1.71060

Purity/Quality:

99% ^*data from raw suppliers

Ethyl2,4-difluorobenzoylformate 97% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 22

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of RARECHEM AL BI 1384

There total 6 articles about RARECHEM AL BI 1384 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

2,4-difluorobromobenzene (348-57-2) + oxalic acid diethyl ester (95-92-1) → ethyl 2-(2,4-difluorophenyl)-2-oxoacetate (157372-95-7)

Guidance literature:

2,4-difluorobromobenzene; With iodine; magnesium; In tetrahydrofuran; at 40 ℃; for 2.5h; Inert atmosphere;

oxalic acid diethyl ester; In tetrahydrofuran; at -40 ℃; for 3.5h;

Reference yield:

C10H10F2O3 (929885-42-7) → ethyl 2-(2,4-difluorophenyl)-2-oxoacetate (157372-95-7)

Guidance literature:

With acetic anhydride; In dimethyl sulfoxide; at 90 ℃; for 3.5h;

Reference yield:

oxalic acid diethyl ester (95-92-1) + (2,4-difluorophenyl)magnesium bromide (144025-04-7) → ethyl 2-(2,4-difluorophenyl)-2-oxoacetate (157372-95-7)

Guidance literature:

In tetrahydrofuran; at -40 ℃; for 1h;

upstream raw materials:

C₁₀H₁₀F₂O₃

2,4-difluorobromobenzene

oxalic acid diethyl ester

(2,4-difluorophenyl)magnesium bromide

Downstream raw materials:

C₁₀H₉F₂NO₃