ethyl 2-(((4-amino-6-chloropyrimidin-5-yl)methyl)(cyclohexyl)amino)acetate

Base Information

Chemical Name:ethyl 2-(((4-amino-6-chloropyrimidin-5-yl)methyl)(cyclohexyl)amino)acetate
CAS No.:1341216-83-8
Molecular Formula:C15H23ClN4O2
Molecular Weight:326.82172
Hs Code.:
Mol file:1341216-83-8.mol

Synonyms:ethyl 2-(((4-amino-6-chloropyrimidin-5-yl)methyl)(cyclohexyl)amino)acetate

Suppliers and Price of ethyl 2-(((4-amino-6-chloropyrimidin-5-yl)methyl)(cyclohexyl)amino)acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of ethyl 2-(((4-amino-6-chloropyrimidin-5-yl)methyl)(cyclohexyl)amino)acetate

Chemical Property:

Melting Point:97 - 99 °C
PSA：81.34000
LogP:2.99120

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

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Technology Process of ethyl 2-(((4-amino-6-chloropyrimidin-5-yl)methyl)(cyclohexyl)amino)acetate

There total 2 articles about ethyl 2-(((4-amino-6-chloropyrimidin-5-yl)methyl)(cyclohexyl)amino)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1341216-79-2
(4-amino-6-chloropyrimidin-5-yl)methanol

: 1341216-83-8
ethyl 2-(((4-amino-6-chloropyrimidin-5-yl)methyl)(cyclohexyl)amino)acetate

Guidance literature:: Multi-step reaction with 2 steps

1: thionyl chloride / dichloromethane / 0.17 h / 0 - 20 °C

2: N-ethyl-N,N-diisopropylamine / acetonitrile / 0 - 20 °C

With thionyl chloride; N-ethyl-N,N-diisopropylamine; In dichloromethane; acetonitrile;
DOI:10.1002/jhet.615

Reference yield:

: 14160-93-1
4-amino-6-chloro-pyrimidine-5-carbaldehyde

: 1341216-83-8
ethyl 2-(((4-amino-6-chloropyrimidin-5-yl)methyl)(cyclohexyl)amino)acetate

Guidance literature:: Multi-step reaction with 3 steps

1: sodium tetrahydroborate / methanol / 0.17 h / 0 - 20 °C

2: thionyl chloride / dichloromethane / 0.17 h / 0 - 20 °C

3: N-ethyl-N,N-diisopropylamine / acetonitrile / 0 - 20 °C

With sodium tetrahydroborate; thionyl chloride; N-ethyl-N,N-diisopropylamine; In methanol; dichloromethane; acetonitrile;
DOI:10.1002/jhet.615