4-Oxo-chroman-8-carboxylic acid

Base Information

Chemical Name:4-Oxo-chroman-8-carboxylic acid
CAS No.:90921-10-1
Molecular Formula:C10H8O4
Molecular Weight:192.171
Hs Code.:
DSSTox Substance ID:DTXSID601224057
Mol file:90921-10-1.mol

Synonyms:90921-10-1;4-Oxochroman-8-carboxylic acid;4-oxo-chroman-8-carboxylic acid;4-Oxochroman-8-carboxylicacid;4-oxo-3,4-dihydro-2H-1-benzopyran-8-carboxylic acid;4-oxo-8-Chromancarboxylic Acid;3,4-Dihydro-4-oxo-2H-1-benzopyran-8-carboxylic acid;SCHEMBL6836766;DTXSID601224057;AM9495;AKOS006373329;4-OXOCHROMANE-8-CARBOXYLIC ACID;CS-0372991;4-oxo-2,3-dihydrochromene-8-carboxylic acid;EN300-117187;Y12745;4-oxo-3,4-dihydro-2h-chromene-8-carboxylic acid

Suppliers and Price of 4-Oxo-chroman-8-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-oxo-8-ChromancarboxylicAcid
1g
$ 1540.00

Total 9 raw suppliers

Chemical Property of 4-Oxo-chroman-8-carboxylic acid

Chemical Property:

Melting Point:206 °C
Boiling Point:416.4±45.0 °C(Predicted)
PKA:3.07±0.20(Predicted)
PSA：63.60000
Density:1.409±0.06 g/cm3(Predicted)
LogP:1.35000
XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:192.04225873
Heavy Atom Count:14
Complexity:261

Purity/Quality:

99%, ^*data from raw suppliers

4-oxo-8-ChromancarboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COC2=C(C1=O)C=CC=C2C(=O)O
Uses 4-oxo-8-Chromancarboxylic Acid has been used in the synthesis of New 4-benzopyranone derivatives with analgesic, antiinflammatory and platelet antiaggregating activities.

Technology Process of 4-Oxo-chroman-8-carboxylic acid

There total 9 articles about 4-Oxo-chroman-8-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 33.0%

: 91344-89-7
methyl 4-oxochromane-8-carboxylate

: 90921-10-1
acide chromannone-4 carboxylique-8

Guidance literature:: With lithium hydroxide monohydrate; In methanol; water; at 20 ℃; for 2h;

Reference yield:

: 119-36-8,8024-54-2
methyl salicylate

: 90921-10-1
acide chromannone-4 carboxylique-8

Guidance literature:: Multi-step reaction with 4 steps

1: potassium carbonate / N,N-dimethyl-formamide / 16 h / 60 °C

2: chromium(VI) oxide; sulfuric acid / water; acetone / 3.33 h / 0 - 20 °C

3: chlorosulfonic acid / 1 h / 0 °C

4: lithium hydroxide monohydrate / water; methanol / 2 h / 20 °C

With chromium(VI) oxide; chlorosulfonic acid; lithium hydroxide monohydrate; sulfuric acid; potassium carbonate; In methanol; water; N,N-dimethyl-formamide; acetone;

Reference yield:

: 25268-05-7
3-(2-methylphenoxy)propanenitrile

: 90921-10-1
acide chromannone-4 carboxylique-8

Guidance literature:: Multi-step reaction with 3 steps

1: HCl, CH₃COOH

2: KMnO₄ / alkaline medium

3: conc. H₂SO₄

With hydrogenchloride; potassium permanganate; acetic acid; sulfuric acid;