2-[(9R)-9-(pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl]acetaldehyde

Base Information

Chemical Name:2-[(9R)-9-(pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl]acetaldehyde
CAS No.:1401031-28-4
Molecular Formula:C16H21NO2
Molecular Weight:259.343
Hs Code.:
Mol file:1401031-28-4.mol

Synonyms:2-[(9R)-9-(pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl]acetaldehyde

Suppliers and Price of 2-[(9R)-9-(pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl]acetaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-[(9R)-9-(pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl]acetaldehyde

Chemical Property:

PSA：39.19000
LogP:3.03160

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-[(9R)-9-(pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl]acetaldehyde

There total 11 articles about 2-[(9R)-9-(pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl]acetaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 1401031-38-6,1401031-37-5
2-[(9R)-9-(pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl]acetonitrile

: 1401031-28-4
2-[(9R)-9-(pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl]acetaldehyde

Guidance literature:: With diisobutylaluminium hydride; In toluene; at -78 ℃; for 1.5h;

Reference yield:

: C₁₈H₂₆N₂O₃

: 1401031-28-4
2-[(9R)-9-(pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl]acetaldehyde

Guidance literature:: With sodium bis(2-methoxyethoxy)aluminium dihydride; In toluene; at -45 - -35 ℃; Inert atmosphere;

Reference yield:

: 1401031-37-5
2-[9-(pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl]acetonitrile

: 1401031-28-4
2-[(9R)-9-(pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl]acetaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: Column: Chiralpak AD-H (Daicel) / methanol; carbon dioxide / 40 °C / Supercritical conditions; liquid CO₂

2: diisobutylaluminium hydride / toluene / 1.5 h / -78 °C

With diisobutylaluminium hydride; In methanol; carbon dioxide; toluene;