Sodium 1-hexanesulfonate

Base Information

• Chemical Name: Sodium 1-hexanesulfonate
• CAS No.: 2832-45-3
• Molecular Formula: C6H13NaO3S
• Molecular Weight: 188.223
• Hs Code.: 29041000
• Mol file: 2832-45-3.mol

Synonyms:1-Hexanesulfonicacid, sodium salt (8CI,9CI);Hexylsulfonic acid sodium salt;Sodium 1-hexylsulfonate;Sodium hexanesulfonate;Sodiumhexyl sulfonate;Sodium n-hexylsulfonate;Sodium-1-hexane sulfonate;

Chemical Property of Sodium 1-hexanesulfonate

Chemical Property:

• Appearance/Colour: White crystalline solid
• Melting Point: >300 °C(lit.)
• PSA: 65.58000
• Density: 1.017 g/cm³
• LogP: 2.19270
• Storage Temp.: Store at +5°C to +30°C.
• Solubility.: H2O: soluble0.1M at 20°C, clear, colorless
• Water Solubility.: Soluble in water.

Purity/Quality:

99% ^*data from raw suppliers

1-Hexanesulfonic Acid Sodium Salt ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 37/39-26-36/37/39-27-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: suzuki reaction Sodium 1-hexanesulfonate is used as a base in the organic coupling reactions such as Suzuki coupling reactions. It is used as an ion pairing reagent for HPLC and involved in the analysis of peptides and proteins. It is also used in high performance capillary electrophoresis analysis of peptides.

Technology Process of Sodium 1-hexanesulfonate

There total 9 articles about Sodium 1-hexanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

Sodium trans-1-hexene-1-sulfonate (83633-60-7) → sodium hexyl sulfate (2832-45-3)

Guidance literature:

With hydrogen; palladium on activated charcoal; In water; for 2h; under 38268.9 Torr;

DOI:10.1021/je00031a036

Reference yield:

1-hexene (592-41-6,25067-06-5) → sodium hexyl sulfate (2832-45-3)

Guidance literature:

Multi-step reaction with 6 steps

1: 45 percent / benzoyl peroxide / benzene / 16 h / Heating

2: 97 percent / NaI / acetone / 1 h / Ambient temperature

3: 91 percent / PCl₅

4: 84 percent / Et₃N / benzene

5: 87 percent / NaHCO₃ / H₂O / 1 h / Heating

6: 98 percent / H₂ / 10percent Pd/C / H₂O / 2 h / 38268.9 Torr

With phosphorus pentachloride; hydrogen; sodium hydrogencarbonate; triethylamine; sodium iodide; dibenzoyl peroxide; palladium on activated charcoal; In water; acetone; benzene;

DOI:10.1021/je00031a036

Reference yield:

trans-1-Hexene-1-sulfonyl chloride (83633-58-3) → sodium hexyl sulfate (2832-45-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 87 percent / NaHCO₃ / H₂O / 1 h / Heating

2: 98 percent / H₂ / 10percent Pd/C / H₂O / 2 h / 38268.9 Torr

With hydrogen; sodium hydrogencarbonate; palladium on activated charcoal; In water;

DOI:10.1021/je00031a036

upstream raw materials:

Sodium trans-1-hexene-1-sulfonate

1-bromo-hexane

1-hexene

trans-1-Hexene-1-sulfonyl chloride

Downstream raw materials:

2-phenyl-9-tetradecyl-benzo[8,9]quinolizino[4,5,6,7-fed]phenanthridinylium hexanesulfonate

hexane-1-sulfonyl fluoride

Hexyl-sulfonsaeure-<4-nitro-phenylester>

1-hexanesulfonyl chloride

Refernces

• 1、 Herkstroeter, William G.,Martic, Peter A.,Evans, Ted R.,Farid, Samir. "Cyclodextrin Inclusion Complexes of 1-Pyrenebutyrate: The Role of Coinclusion of Amphiphiles". . p. 3275 - 3280. Retrieved 2007/10/02.