[2-HYDROXYIMINO-2-(3-METHOXY-PHENYL)-ETHYL]-CARBAMIC ACID TERT-BUTYL ESTER

Base Information

• Chemical Name: [2-HYDROXYIMINO-2-(3-METHOXY-PHENYL)-ETHYL]-CARBAMIC ACID TERT-BUTYL ESTER
• CAS No.: 912762-53-9
• Molecular Formula: C₁₄H₂₀N₂O₄
• Molecular Weight: 280.324
• Hs Code.: 2928000090
• Mol file: 912762-53-9.mol

Synonyms:[2-HYDROXYIMINO-2-(3-METHOXY-PHENYL)-ETHYL]-CARBAMIC ACID TERT-BUTYL ESTER

Chemical Property of [2-HYDROXYIMINO-2-(3-METHOXY-PHENYL)-ETHYL]-CARBAMIC ACID TERT-BUTYL ESTER

Chemical Property:

• Vapor Pressure: 1.01E-08mmHg at 25°C
• Boiling Point: 445.6°C at 760 mmHg
• Flash Point: 223.3°C
• PSA: 80.15000
• Density: 1.12g/cm³
• LogP: 2.78910

Purity/Quality:

97% ^*data from raw suppliers

TERT-BUTYL-N-[(2Z)-2-(HYDROXYIMINO)-2-(3-METHOXYPHENYL)ETHYL]CARBAMATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of [2-HYDROXYIMINO-2-(3-METHOXY-PHENYL)-ETHYL]-CARBAMIC ACID TERT-BUTYL ESTER

There total 3 articles about [2-HYDROXYIMINO-2-(3-METHOXY-PHENYL)-ETHYL]-CARBAMIC ACID TERT-BUTYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-bromo-3'-methoxyacetophenone (5000-65-7) → C14H20N2O4 (912762-53-9)

Guidance literature:

Multi-step reaction with 3 steps

1.1: hexamethylenetetramine; sodium iodide / ethanol / 24 h

1.2: 5 h / Reflux

2.1: sodium hydrogencarbonate / methanol / 12 h

3.1: hydroxylamine hydrochloride; pyridine / ethanol / 3 h

With pyridine; hexamethylenetetramine; hydroxylamine hydrochloride; sodium hydrogencarbonate; sodium iodide; In methanol; ethanol; 1.1: |Delepine Amine Synthesis / 1.2: |Delepine Amine Synthesis;

DOI:10.1016/j.bmcl.2016.03.043

Reference yield:

2-amino-1-(3-methoxyphenyl)ethan-1-one (189506-47-6) → C14H20N2O4 (912762-53-9)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium hydrogencarbonate / methanol / 12 h

2: hydroxylamine hydrochloride; pyridine / ethanol / 3 h

With pyridine; hydroxylamine hydrochloride; sodium hydrogencarbonate; In methanol; ethanol;

DOI:10.1016/j.bmcl.2016.03.043

Reference yield:

tert-butyl (2-(3-methoxyphenyl)-2-oxoethyl)carbamate (912762-33-5) → C14H20N2O4 (912762-53-9)

Guidance literature:

With pyridine; hydroxylamine hydrochloride; In ethanol; for 3h;

DOI:10.1016/j.bmcl.2016.03.043

upstream raw materials:

2-bromo-3'-methoxyacetophenone

2-amino-1-(3-methoxyphenyl)ethan-1-one

tert-butyl (2-(3-methoxyphenyl)-2-oxoethyl)carbamate

Refernces