(6-Amino-5-(trifluoromethyl)pyridin-3-yl)boronic acid

Base Information

Chemical Name:(6-Amino-5-(trifluoromethyl)pyridin-3-yl)boronic acid
CAS No.:1189126-37-1
Molecular Formula:C6H6BF3N2O2
Molecular Weight:205.9302496
Hs Code.:2933399090
DSSTox Substance ID:DTXSID20695937
Wikidata:Q82625326
Mol file:1189126-37-1.mol

Synonyms:1189126-37-1;2-AMINO-3-(TRIFLUOROMETHYL)-PYRIDINE-5-BORONIC ACID;(6-Amino-5-(trifluoromethyl)pyridin-3-yl)boronic acid;[6-amino-5-(trifluoromethyl)pyridin-3-yl]boronic acid;6-amino-5-(trifluoromethyl)pyridin-3-ylboronic acid;2-Amino-3-(trifluoromethyl)pyridine-5-boronic acid;C6H6BF3N2O2;SCHEMBL357802;DTXSID20695937;SB31603;CS-0441972;FT-0702051;EN300-8675587

Suppliers and Price of (6-Amino-5-(trifluoromethyl)pyridin-3-yl)boronic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
[6-Amino-5-(trifluoromethyl)pyridin-3-yl]boronic acid 97%
1 g
$ 1734.00

SynQuest Laboratories
[6-Amino-5-(trifluoromethyl)pyridin-3-yl]boronic acid 97%
250 mg
$ 643.00

J&W Pharmlab
2-Amino-3-(trifluoromethyl)-pyridine-5-boronicacid 96%
5g
$ 598.00

J&W Pharmlab
2-Amino-3-(trifluoromethyl)-pyridine-5-boronicacid 96%
1g
$ 198.00

J&W Pharmlab
2-Amino-3-(trifluoromethyl)-pyridine-5-boronicacid 96%
500mg
$ 149.00

Alichem
2-Amino-3-(trifluoromethyl)pyridine-5-boronicacid
500mg
$ 1121.77

Alichem
2-Amino-3-(trifluoromethyl)pyridine-5-boronicacid
250mg
$ 778.37

AHH
6-amino-5-(trifluoromethyl)pyridin-3-ylboronicacid 97%
1g
$ 695.00

Total 7 raw suppliers

Chemical Property of (6-Amino-5-(trifluoromethyl)pyridin-3-yl)boronic acid

Chemical Property:

Boiling Point:364.2±52.0 °C(Predicted)
PKA:3.25±0.11(Predicted)
PSA：79.37000
Density:1.51±0.1 g/cm3(Predicted)
LogP:-0.05640
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:1
Exact Mass:206.0474421
Heavy Atom Count:14
Complexity:202

Purity/Quality:

97% ^*data from raw suppliers

[6-Amino-5-(trifluoromethyl)pyridin-3-yl]boronic acid 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B(C1=CC(=C(N=C1)N)C(F)(F)F)(O)O

Technology Process of (6-Amino-5-(trifluoromethyl)pyridin-3-yl)boronic acid

There total 2 articles about (6-Amino-5-(trifluoromethyl)pyridin-3-yl)boronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 79456-34-1
5-bromo-3-(trifluoromethyl)pyridin-2-amine

: 1189126-37-1
6-amino-5-(trifluoromethyl)pyridin-3-ylboronic acid

Guidance literature:: With potassium acetate; bis(pinacol)diborane; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; In 1,4-dioxane; for 8h; Inert atmosphere; Reflux;

Reference yield:

: 183610-70-0
2-amino-3-trifluoromethylpyridine

: 1189126-37-1
6-amino-5-(trifluoromethyl)pyridin-3-ylboronic acid

Guidance literature:: Multi-step reaction with 2 steps

1: bromine; acetic acid / 2 h / 20 °C

2: potassium acetate; bis(pinacol)diborane / dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂ / 1,4-dioxane / 8 h / Inert atmosphere; Reflux

With bromine; potassium acetate; acetic acid; bis(pinacol)diborane; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; In 1,4-dioxane;