Dehydro Norketamine-d4

Base Information

Chemical Name:Dehydro Norketamine-d4
CAS No.:1246816-68-1
Molecular Formula:C12H12ClNO
Molecular Weight:221.68278
Hs Code.:
Mol file:1246816-68-1.mol

Synonyms:Dehydro Norketamine-d4;5,6-DehydronorketaMine-d4;6-AMino-6-(2-chlorophenyl-d4)-2-cyclohexen-1-one

Suppliers and Price of Dehydro Norketamine-d4

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Dehydro Norketamine-d4

Chemical Property:

PSA：43.09000
LogP:3.11340

Purity/Quality:: 95%+ or 98%+ ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses A labelled metabolite of Ketamine (K165300).

Technology Process of Dehydro Norketamine-d4

There total 9 articles about Dehydro Norketamine-d4 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₂H₉⁽²⁾H₄BrClNO

: 1246816-68-1
6-amino-6-(2-[2H₄]-chlorophenyl)cyclohex-2-enone

Guidance literature:: With DBN; In acetonitrile; for 25h; Reflux;
DOI:10.1016/j.bmcl.2011.08.021

Reference yield:

: C₁₂H₁₀⁽²⁾H₄BrClO

: 1246816-68-1
6-amino-6-(2-[2H₄]-chlorophenyl)cyclohex-2-enone

Guidance literature:: Multi-step reaction with 5 steps

1.1: pyridinium chlorochromate / dichloromethane / 13 h / 20 °C

2.1: sodium azide / dimethyl sulfoxide / 5 h / 25 °C

3.1: triphenylphosphine / tetrahydrofuran / 12 h / 65 °C

3.2: 3 h / Reflux

4.1: hydrogen bromide; bromine / water / 70 °C

5.1: DBN / acetonitrile / 25 h / Reflux

With sodium azide; DBN; hydrogen bromide; bromine; triphenylphosphine; pyridinium chlorochromate; In tetrahydrofuran; dichloromethane; water; dimethyl sulfoxide; acetonitrile; 3.1: Staudinger reaction / 3.2: Staudinger reaction;
DOI:10.1016/j.bmcl.2011.08.021

Reference yield:

: 1336986-06-1
1-(2-[2H₄]-chlorophenyl)cyclohexene

: 1246816-68-1
6-amino-6-(2-[2H₄]-chlorophenyl)cyclohex-2-enone

Guidance literature:: Multi-step reaction with 7 steps

1.1: sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid / dichloromethane / 0 - 25 °C

2.1: water; hydrogen bromide / chloroform / 0.5 h / 20 °C

3.1: pyridinium chlorochromate / dichloromethane / 13 h / 20 °C

4.1: sodium azide / dimethyl sulfoxide / 5 h / 25 °C

5.1: triphenylphosphine / tetrahydrofuran / 12 h / 65 °C

5.2: 3 h / Reflux

6.1: hydrogen bromide; bromine / water / 70 °C

7.1: DBN / acetonitrile / 25 h / Reflux

With sodium azide; DBN; water; hydrogen bromide; bromine; sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid; triphenylphosphine; pyridinium chlorochromate; In tetrahydrofuran; dichloromethane; chloroform; water; dimethyl sulfoxide; acetonitrile; 5.1: Staudinger reaction / 5.2: Staudinger reaction;
DOI:10.1016/j.bmcl.2011.08.021