4-Chloro-5-methoxy-2-(2-pyridinyl)pyrimidine

Base Information

Chemical Name:4-Chloro-5-methoxy-2-(2-pyridinyl)pyrimidine
CAS No.:321432-82-0
Molecular Formula:C10H8ClN3O
Molecular Weight:221.646
Hs Code.:2933990090
DSSTox Substance ID:DTXSID30376987
Wikidata:Q82165980
Mol file:321432-82-0.mol

Synonyms:321432-82-0;4-CHLORO-5-METHOXY-2-(2-PYRIDINYL)PYRIMIDINE;4-chloro-5-methoxy-2-(pyridin-2-yl)pyrimidine;4-chloro-5-methoxy-2-pyridin-2-ylpyrimidine;4-CHLORO-5-METHOXY-2-(2-PYRIDINYL)-PYRIMIDINE;SCHEMBL1442223;DTXSID30376987;BTHRCJACYHBCHX-UHFFFAOYSA-N;CS-D1282;WMA43282;MFCD00215412;AKOS005069832;1J-324S;FT-0761393;A875690;4-chloro-5-methoxy-2-(2-pyridinyl)pyrimidine, AldrichCPR

Suppliers and Price of 4-Chloro-5-methoxy-2-(2-pyridinyl)pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
4-Chloro-5-methoxy-2-(2-pyridinyl)pyrimidine >95%
250mg
$ 296.00

Matrix Scientific
4-Chloro-5-methoxy-2-(2-pyridinyl)pyrimidine >95%
5g
$ 1950.00

Crysdot
4-Chloro-5-methoxy-2-(pyridin-2-yl)pyrimidine 95+%
5g
$ 1984.00

Crysdot
4-Chloro-5-methoxy-2-(pyridin-2-yl)pyrimidine 95+%
1g
$ 664.00

Chemenu
4-Chloro-5-methoxy-2-(pyridin-2-yl)pyrimidine 95%
5g
$ 1855.00

Chemenu
4-Chloro-5-methoxy-2-(pyridin-2-yl)pyrimidine 95%
1g
$ 621.00

Apolloscientific
4-Chloro-5-methoxy-2-(pyridin-2-yl)pyrimidine 95%
1g
$ 580.00

Alichem
4-Chloro-5-methoxy-2-(pyridin-2-yl)pyrimidine
250mg
$ 341.33

Alichem
4-Chloro-5-methoxy-2-(pyridin-2-yl)pyrimidine
1g
$ 844.82

Alfa Aesar
4-Chloro-5-methoxy-2-(2-pyridyl)pyrimidine, 97%
250mg
$ 194.00

Total 11 raw suppliers

Chemical Property of 4-Chloro-5-methoxy-2-(2-pyridinyl)pyrimidine

Chemical Property:

Boiling Point:260.8±22.0 °C(Predicted)
PKA:-0.31±0.19(Predicted)
PSA：47.90000
Density:1.301±0.06 g/cm3(Predicted)
LogP:2.20060
XLogP3:1.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:221.0355896
Heavy Atom Count:15
Complexity:205

Purity/Quality:

97% ^*data from raw suppliers

4-Chloro-5-methoxy-2-(2-pyridinyl)pyrimidine >95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CN=C(N=C1Cl)C2=CC=CC=N2

Technology Process of 4-Chloro-5-methoxy-2-(2-pyridinyl)pyrimidine

There total 4 articles about 4-Chloro-5-methoxy-2-(2-pyridinyl)pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 321432-75-1
C₁₀H₉N₃O₂

: 321432-82-0
4-chloro-5-methoxy-2-(pyridin-2-yl)pyrimidine

Guidance literature:: With trichlorophosphate; for 1.5h; Reflux;

Reference yield: 48.0%

: 321432-75-1
5-Methoxy-2-pyridine-2-yl-3H-pyrimidin-4-one

: 321432-82-0
4-chloro-5-methoxy-2-(pyridin-2-yl)pyrimidine

Guidance literature:: With trichlorophosphate; In N,N-dimethyl-aniline;

Reference yield:

: 100-70-9,1232006-36-8
2-Cyanopyridine

: 321432-82-0
4-chloro-5-methoxy-2-(pyridin-2-yl)pyrimidine

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium methylate / methanol / 20 °C

1.2: 5 h / Reflux

2.1: methanol / 5.5 h / 10 - 63 °C

2.2: pH 4 - 5

3.1: trichlorophosphate / 1.5 h / Reflux

With sodium methylate; trichlorophosphate; In methanol;