1-[10-[3-(Dimethylamino)propyl]phenothiazin-2-yl]ethanol

Base Information

Chemical Name:1-[10-[3-(Dimethylamino)propyl]phenothiazin-2-yl]ethanol
CAS No.:73644-43-6
Molecular Formula:C19H24N2OS
Molecular Weight:328.47166
Hs Code.:
DSSTox Substance ID:DTXSID90335454
Nikkaji Number:J1.152.126F
Mol file:73644-43-6.mol

Synonyms:2-(1-hydroxyethyl)promazine;2-OH-promazine

Suppliers and Price of 1-[10-[3-(Dimethylamino)propyl]phenothiazin-2-yl]ethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(1-Hydroxyethyl)Promazine
50mg
$ 350.00

TRC
2-(1-Hydroxyethyl)Promazine
10mg
$ 135.00

Total 4 raw suppliers

Chemical Property of 1-[10-[3-(Dimethylamino)propyl]phenothiazin-2-yl]ethanol

Chemical Property:

Boiling Point:230-240 °C(Press: 0.05 Torr)
PKA:14.12±0.20(Predicted)
PSA：52.01000
Density:1.164±0.06 g/cm3(Predicted)
LogP:4.35930
Storage Temp.:Refrigerator
Solubility.:Acetonitrile (Slightly), DMSO (Slightly), Methanol (Slightly)
XLogP3:3.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:328.16093457
Heavy Atom Count:23
Complexity:378

Purity/Quality:

97% ^*data from raw suppliers

2-(1-Hydroxyethyl)Promazine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C1=CC2=C(C=C1)SC3=CC=CC=C3N2CCCN(C)C)O
Uses A metabolite of Acepromazine (A130900).

Technology Process of 1-[10-[3-(Dimethylamino)propyl]phenothiazin-2-yl]ethanol

There total 2 articles about 1-[10-[3-(Dimethylamino)propyl]phenothiazin-2-yl]ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 61-00-7
acetopromazine

: 73644-43-6
1-[10-(3-dimethylamino-propyl)-phenothiazin-2-yl]-ethanol

Guidance literature:: With lithium aluminium tetrahydride; diethyl ether;

Reference yield:

: 59995-97-0
2-acetyl-phenothiazine-10-carboxylic acid 3-dimethylamino-propyl ester

: 73644-43-6
1-[10-(3-dimethylamino-propyl)-phenothiazin-2-yl]-ethanol

Guidance literature:: Multi-step reaction with 2 steps

1: 1,3-dimethoxy-benzene; copper-powder

2: LiAlH₄; diethyl ether

With lithium aluminium tetrahydride; diethyl ether; copper; 1,3-Dimethoxybenzene;