2-Fluoro-pyridine-3-sulphonylchloride

Base Information

• Chemical Name: 2-Fluoro-pyridine-3-sulphonylchloride
• CAS No.: 1089330-70-0
• Molecular Formula: C₅H₃ClFNO₂S
• Molecular Weight: 195.602
• Hs Code.: 2933399090
• Mol file: 1089330-70-0.mol

Synonyms:2-Fluoro-pyridine-3-sulphonylchloride

Chemical Property of 2-Fluoro-pyridine-3-sulphonylchloride

Chemical Property:

• PSA: 55.41000
• LogP: 2.22900

Purity/Quality:

99% ^*data from raw suppliers

2-Fluoro-pyridine-3-sulfonylChloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Fluoro-pyridine-3-sulphonylchloride

There total 1 articles about 2-Fluoro-pyridine-3-sulphonylchloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-fluoro-3-pyridinylamine (1597-33-7) → 2-fluoropyridine-3-sulfonyl chloride (1089330-70-0)

Guidance literature:

2-fluoro-3-pyridinylamine; With hydrogenchloride; acetic acid; sodium nitrite; In dichloromethane; water; at 0 ℃; for 0.333333h;

With sulfur dioxide; copper(II) choride dihydrate; In dichloromethane; water; at 0 ℃; for 3h;

Reference yield: 84.0%

2-fluoropyridine-3-sulfonyl chloride (1089330-70-0) + aniline (62-53-3) → 2-fluoropyridine-3-sulfonic acid phenylamide (1285712-28-8)

Guidance literature:

2-fluoropyridine-3-sulfonyl chloride; With pyridine; at 0 ℃; Inert atmosphere;

aniline; at 0 - 20 ℃; for 16h; Inert atmosphere;

DOI:10.1055/s-0030-1258302

upstream raw materials:

2-fluoro-3-pyridinylamine

Downstream raw materials:

2-fluoropyridine-3-sulfonic acid phenylamide

Refernces