1-((1aR,7aR)-7,7-diMethyl-7,7a-dihydro-1aH-oxireno[2,3-c]chroMen-3-yl)ethanone

Base Information

• Chemical Name: 1-((1aR,7aR)-7,7-diMethyl-7,7a-dihydro-1aH-oxireno[2,3-c]chroMen-3-yl)ethanone
• CAS No.: 171596-62-6
• Molecular Formula: C₁₃H₁₄O₃
• Molecular Weight: 218.252
• Mol file: 171596-62-6.mol

Synonyms:1-((1aR,7aR)-7,7-diMethyl-7,7a-dihydro-1aH-oxireno[2,3-c]chroMen-3-yl)ethanone;(3R,4R)-6-acetyl-2,2-dimethyl-3,4-epoxy-2H-1-benzopyran

Chemical Property of 1-((1aR,7aR)-7,7-diMethyl-7,7a-dihydro-1aH-oxireno[2,3-c]chroMen-3-yl)ethanone

Chemical Property:

• PSA: 38.83000
• LogP: 2.50010

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-((1aR,7aR)-7,7-diMethyl-7,7a-dihydro-1aH-oxireno[2,3-c]chroMen-3-yl)ethanone

There total 3 articles about 1-((1aR,7aR)-7,7-diMethyl-7,7a-dihydro-1aH-oxireno[2,3-c]chroMen-3-yl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

desmethoxyencecalin (19013-07-1) → (3R,4R)-6-acetyl-2,2-dimethyl-3,4-epoxy-2H-1-benzopyran (171596-62-6)

Guidance literature:

With sodium hydroxide; sodium hypochlorite; sodium dihydrogenphosphate; (R)-1-phenyl-1,2-bis(3,5-di-tert-butyl-salicylideamino)ethane-manganese (III) chloride; In dichloromethane; water; at 20 ℃; pH=11.3;

Reference yield: 79.0%

→ (3R,4R)-6-acetyl-2,2-dimethyl-3,4-epoxy-2H-1-benzopyran (171596-62-6)

Guidance literature:

Reference yield:

desmethoxyencecalin (19013-07-1) → (3R,4R)-6-acetyl-2,2-dimethyl-3,4-epoxy-2H-1-benzopyran (171596-62-6) + (3S,4S)-6-acetyl-2,2-dimethyl-3,4-epoxy-2H-1-benzopyran (178458-56-5)

Guidance literature:

With sodium hypochlorite; isoquinoline N-oxide; (S,S)-manganese(III) salen; for 1.5h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; Ambient temperature;

DOI:10.1016/0040-4039(96)00683-1

upstream raw materials:

desmethoxyencecalin

Downstream raw materials:

(3R,4S)-6-Acetyl-4-(4-fluorobenzamido)-3,4-dihydro-2,2-dimethyl-3-hydroxy-2H-1-benzopyran

trans-6-Acetyl-4-amino-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran