NA

Base Information

• Chemical Name: NA
• CAS No.: 91354-09-5
• Molecular Formula: C₁₂H₈BrCl
• Molecular Weight: 267.553
• Mol file: 91354-09-5.mol

Synonyms:

Chemical Property of NA

Chemical Property:

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of NA

There total 7 articles about NA which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

3-iodochlorobenzene (625-99-0) + 1,4-bromoiodobenzene (589-87-7) → 4-bromo-3'-chloro-1,1'-biphenyl (91354-09-5)

Guidance literature:

3-iodochlorobenzene; With TurboGrignard; In tetrahydrofuran; at -20 ℃; for 0.333333h;

1,4-bromoiodobenzene; bis(dibenzylideneacetone)-palladium⁽⁰⁾; In tetrahydrofuran; toluene; at -30 ℃; for 12h; Further stages.;

DOI:10.1021/ja070830d

Reference yield: 40.0%

1,4-bromoiodobenzene (589-87-7) + 3-chlorophenylboronic acid (63503-60-6) → 4-bromo-3'-chloro-1,1'-biphenyl (91354-09-5)

Guidance literature:

With palladium diacetate; potassium carbonate; triphenylphosphine; In ethanol; water; toluene; at 80 ℃; for 20h;

DOI:10.1021/acs.jmedchem.5b00518

Reference yield: 30.0%

ponicidin (52617-37-5) + acetic anhydride (108-24-7) → ponicidin 1,6,7-triacetate

Guidance literature:

With pyridine; dmap; at 20 ℃; for 0.5h;

DOI:10.1016/j.steroids.2006.10.004

upstream raw materials:

1,6-di-p-bromophenyl-3,4-diacetyl-1,5-hexazadiene

chlorobenzene

4'-bromo-[1,1'-biphenyl]-3-amine

ponicidin

Downstream raw materials:

3'-Chlor-4-tritium-biphenyl