4-Fluoro-2-(trifluoromethoxy)aniline

Base Information

Chemical Name:4-Fluoro-2-(trifluoromethoxy)aniline
CAS No.:123572-66-7
Molecular Formula:C7H5F4NO
Molecular Weight:195.116
Hs Code.:
European Community (EC) Number:815-018-1
Mol file:123572-66-7.mol

Synonyms:4-fluoro-2-(trifluoromethoxy)aniline;123572-66-7;MFCD15527447;SCHEMBL2544959;QFDKCJQODJFZID-UHFFFAOYSA-N;AKOS015957246;JS-4960;SY228806;CS-0318680;D96230;A902944

Suppliers and Price of 4-Fluoro-2-(trifluoromethoxy)aniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 9 raw suppliers

Chemical Property of 4-Fluoro-2-(trifluoromethoxy)aniline

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:1
Exact Mass:195.03072643
Heavy Atom Count:13
Complexity:172

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=C(C=C1F)OC(F)(F)F)N

Technology Process of 4-Fluoro-2-(trifluoromethoxy)aniline

There total 3 articles about 4-Fluoro-2-(trifluoromethoxy)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 123572-65-6
4-fluoro-1-nitro-2-(trifluoromethoxy)benzene

: 123572-66-7
4-fluoro-2-(trifluoromethoxy)benzenamine

Guidance literature:: With palladium on activated charcoal; hydrogen; In methanol; for 2h; Reagent/catalyst; Solvent; Inert atmosphere;

Reference yield:

: 1077-01-6
meta-fluoro(trifluoromethoxy)benzene

: 123572-66-7
4-fluoro-2-(trifluoromethoxy)benzenamine

Guidance literature:: Multi-step reaction with 2 steps

1: potassium nitrate; sulfuric acid / 3 h / 0 °C / Cooling with ice

2: tin(ll) chloride / ethanol; water / 20 °C / Cooling with ice

With sulfuric acid; potassium nitrate; tin(ll) chloride; In ethanol; water;