Ethyl 2-(4-aminocyclohexyl)acetate

Base Information

Chemical Name:Ethyl 2-(4-aminocyclohexyl)acetate
CAS No.:76308-28-6
Molecular Formula:C10H19NO2
Molecular Weight:185.266
Hs Code.:
European Community (EC) Number:616-319-9
DSSTox Substance ID:DTXSID001238521
Nikkaji Number:J1.121.328F,J1.121.329D
Mol file:76308-28-6.mol

Synonyms:Ethyl 2-(4-aminocyclohexyl)acetate;76308-28-6;Ethyl 2-(trans-4-aminocyclohexyl)acetate;343775-23-5;Ethyl trans-2-(4-aminocyclohexyl)acetate;76308-15-1;(trans-4-Aminocyclohexyl)acetic Acid Ethyl Ester;Cyclohexaneacetic acid,4-amino-,ethyl ester,trans-;Oprea1_333732;SCHEMBL227338;SCHEMBL227339;SCHEMBL12536054;SCHEMBL14724821;SBVCDGKSVSHGFL-KYZUINATSA-N;DTXSID001238521;BDA30828;CS-M1352;MFCD01333995;Ethyl2-(cis-4-aminocyclohexyl)acetate;Ethyl 2-(cis-4-aminocyclohexyl)acetate;ethyl trans-(4-amino-cyclohexyl)acetate;DS-11750;CS-0008596;FT-0734585;(trans-4-Aminocyclohexyl)aceticAcidEthylEster;ethyl 2-[(1r,4r)-4-aminocyclohexyl]acetate;ethyl 2-[(1s,4s)-4-aminocyclohexyl]acetate;C76441;D77419;EN300-250694;EN300-23025073;EN300-24209288;Trans-(4-Amino-cyclohexyl)-acetic acid ethyl ester;4alpha-Amino-1alpha-cyclohexaneacetic acid ethyl ester;4beta-Amino-1alpha-cyclohexaneacetic acid ethyl ester

Suppliers and Price of Ethyl 2-(4-aminocyclohexyl)acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(trans-4-Aminocyclohexyl)aceticAcidEthylEster
500mg
$ 165.00

Chemenu
Ethyl2-(trans-4-aminocyclohexyl)acetate 95%
5g
$ 505.00

Chemenu
Ethyl2-(trans-4-aminocyclohexyl)acetate 95%
1g
$ 184.00

American Custom Chemicals Corporation
ETHYL-TRANS-2-(4-AMINOCYCLOHEXYL)ACETATE 95.00%
5MG
$ 505.46

Ambeed
Ethyl2-(trans-4-aminocyclohexyl)acetate 95%
5g
$ 422.00

Ambeed
Ethyl2-(trans-4-aminocyclohexyl)acetate 95%
1g
$ 141.00

Ambeed
Ethyl2-(trans-4-aminocyclohexyl)acetate 95%
250mg
$ 57.00

Ambeed
Ethyl2-(trans-4-aminocyclohexyl)acetate 95%
100mg
$ 38.00

Total 20 raw suppliers

Chemical Property of Ethyl 2-(4-aminocyclohexyl)acetate

Chemical Property:

Vapor Pressure:0.0185mmHg at 25°C
Boiling Point:253.2°C at 760 mmHg
PKA:10.49±0.70(Predicted)
Flash Point:116.8°C
PSA：52.32000
Density:0.984g/cm³
LogP:2.15740
Storage Temp.:Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:185.141578849
Heavy Atom Count:13
Complexity:162

Purity/Quality:

99%, ^*data from raw suppliers

(trans-4-Aminocyclohexyl)aceticAcidEthylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)CC1CCC(CC1)N

Technology Process of Ethyl 2-(4-aminocyclohexyl)acetate

There total 4 articles about Ethyl 2-(4-aminocyclohexyl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: ethyl trans-2-(-4-nitrocyclohexyl)acetate

: 76308-28-6
ethyl 2‐[(1r,4r)‐4‐aminocyclohexyl]acetate

Guidance literature:: With hydrogenchloride; iron; In methanol; for 5h; Reagent/catalyst; Cooling with ice;

Reference yield:

: ethyl 2-{(trans/cis)-4-[(tert-butoxycarbonyl)amino]cyclohexyl}acetate

: 76308-28-6
ethyl 2‐[(1r,4r)‐4‐aminocyclohexyl]acetate

: 76308-15-1
cis-4-aminocyclohexylacetic acid ethyl ester

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 12h; Large scale;
DOI:10.1021/acs.oprd.9b00182

Reference yield:

: 104-03-0
4-nitrobenzeneacetic acid

: 76308-28-6
ethyl 2‐[(1r,4r)‐4‐aminocyclohexyl]acetate

Guidance literature:: Multi-step reaction with 2 steps

1: palladium 10% on activated carbon; hydrogen / water / 72 h / 20 °C / 3102.97 Torr

2: hydrogenchloride / water / 2 h / Reflux

With hydrogenchloride; palladium 10% on activated carbon; hydrogen; In water;
DOI:10.1021/jm401318w