4-(2-NITROPHENOXY)PIPERIDINE HYDROCHLORIDE

Base Information

• Chemical Name: 4-(2-NITROPHENOXY)PIPERIDINE HYDROCHLORIDE
• CAS No.: 1072944-49-0
• Molecular Formula: C11H15ClN2O3
• Molecular Weight: 258.705
• Hs Code.: 2933399090
• Mol file: 1072944-49-0.mol

Synonyms:4-(2-NITROPHENOXY)PIPERIDINE HYDROCHLORIDE;4-(2-NITROPHENOXY)PIPERIDINE, HCL;4-(2-Nitrophenoxy)piperidine hydrochloride (1:1)

Chemical Property of 4-(2-NITROPHENOXY)PIPERIDINE HYDROCHLORIDE

Chemical Property:

• PSA: 67.08000
• LogP: 3.37960

Purity/Quality:

97% ^*data from raw suppliers

4-(2-Nitrophenoxy)piperidineHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-(2-NITROPHENOXY)PIPERIDINE HYDROCHLORIDE

There total 1 articles about 4-(2-NITROPHENOXY)PIPERIDINE HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

4-(2-nitrophenoxy)-piperidine-1-carboxylic acid tert-butyl ester (690632-03-2) → 4-(2-nitro-phenoxy)-piperidine hydrochloride (1072944-49-0)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; at 20 ℃; for 1h;

Reference yield: 72.0%

N-biphenyl-4-yl-malonamic acid (108398-68-1) + 4-(2-nitro-phenoxy)-piperidine hydrochloride (1072944-49-0) → N-biphenyl-4-yl-3-[4-(2-nitrophenoxy)piperidin-1-yl]-3-oxopropionamide (1188372-52-2)

Guidance literature:

N-biphenyl-4-yl-malonamic acid; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 0.0333333h;

4-(2-nitro-phenoxy)-piperidine hydrochloride; In N,N-dimethyl-formamide;

Reference yield: 44.0%

[(5-phenyl-1H-pyrazole-3-carbonyl)-amino]-acetic acid (1188374-41-5) + 4-(2-nitro-phenoxy)-piperidine hydrochloride (1072944-49-0) → 5-phenyl-1H-pyrazole-3-carboxylic acid {2-[4-(2-nitro-phenoxy)-piperidin-1-yl]-2-oxo-ethyl}-amide (1188372-24-8)

Guidance literature:

[(5-phenyl-1H-pyrazole-3-carbonyl)-amino]-acetic acid; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 0.0333333h;

4-(2-nitro-phenoxy)-piperidine hydrochloride; In N,N-dimethyl-formamide;

upstream raw materials:

4-(2-nitrophenoxy)-piperidine-1-carboxylic acid tert-butyl ester

Downstream raw materials:

5-phenyl-1H-pyrazole-3-carboxylic acid {2-[4-(2-nitro-phenoxy)-piperidin-1-yl]-2-oxo-ethyl}-amide

N-biphenyl-4-yl-3-[4-(2-nitrophenoxy)piperidin-1-yl]-3-oxopropionamide

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