Technology Process of 2-(AMinoMethyl)-3-Methylpyrazine hydrochloride
There total 3 articles about 2-(AMinoMethyl)-3-Methylpyrazine hydrochloride which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
hydrazine hydrate;
In
ethanol;
for 3h;
Reflux;
Large scale;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: N-chloro-succinimide; 2,2'-azobis(isobutyronitrile) / chloroform / 0.1 h / 60 °C / Large scale
2.1: potassium carbonate / N,N-dimethyl-formamide / 2 h / 60 °C / Large scale
2.2: 2.5 h / 0.9 - 60 °C / Large scale
3.1: hydrazine hydrate / ethanol / 3 h / Reflux; Large scale
With
N-chloro-succinimide; 2,2'-azobis(isobutyronitrile); potassium carbonate; hydrazine hydrate;
In
ethanol; chloroform; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: potassium carbonate / N,N-dimethyl-formamide / 2 h / 60 °C / Large scale
1.2: 2.5 h / 0.9 - 60 °C / Large scale
2.1: hydrazine hydrate / ethanol / 3 h / Reflux; Large scale
With
potassium carbonate; hydrazine hydrate;
In
ethanol; N,N-dimethyl-formamide;