4-Aminomethyl-2,2-difluoro-1,3-benzodioxole

Base Information

Chemical Name:4-Aminomethyl-2,2-difluoro-1,3-benzodioxole
CAS No.:531508-46-0
Molecular Formula:C8H7F2NO2
Molecular Weight:187.1434864
Hs Code.:2932990090
European Community (EC) Number:819-680-2
DSSTox Substance ID:DTXSID70471667
Nikkaji Number:J1.878.337A
Wikidata:Q82300300
Mol file:531508-46-0.mol

Synonyms:531508-46-0;4-AMINOMETHYL-2,2-DIFLUORO-1,3-BENZODIOXOLE;4-(Aminomethyl)-2,2-difluoro-1,3-benzodioxole;(2,2-difluorobenzo[d][1,3]dioxol-4-yl)methanamine;(2,2-DIFLUORO-1,3-BENZODIOXOL-4-YL)METHANAMINE;(2,2-DIFLUORO-2H-1,3-BENZODIOXOL-4-YL)METHANAMINE;MFCD16617616;1-(2,2-Difluoro-1,3-benzodioxol-4-yl)methanamine;1-(2,2-Difluoro-2H-1,3-benzodioxol-4-yl)methanamine;2,2-difluoro-1,3-Benzodioxole-4-methanamine;1,3-Benzodioxole-4-methanamine, 2,2-difluoro-;SCHEMBL3288378;DTXSID70471667;LZUWIFLVQKZUOO-UHFFFAOYSA-N;AKOS022913373;PB16642;AS-33677;SY026119;CS-0044437;FT-0725893;EN300-307191;(2,2-difluoro-1,3-dioxaindan-4-yl)methanamine;A870812;F1911-4942;4-(Aminomethyl)-2 pound not2-difluoro-1 pound not3-benzodioxole

Suppliers and Price of 4-Aminomethyl-2,2-difluoro-1,3-benzodioxole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,2-Difluoro-1,3-benzodioxole-4-methanamine
500mg
$ 175.00

SynQuest Laboratories
4-Aminomethyl-2,2-difluoro-1,3-benzodioxole
1 g
$ 268.00

Crysdot
(2,2-Difluorobenzo[d][1,3]dioxol-4-yl)methanamine 95+%
5g
$ 536.00

ChemScene
(2,2-Difluorobenzo[d][1,3]dioxol-4-yl)methanamine >99.0%
1g
$ 222.00

ChemScene
(2,2-Difluorobenzo[d][1,3]dioxol-4-yl)methanamine >99.0%
100mg
$ 53.00

ChemScene
(2,2-Difluorobenzo[d][1,3]dioxol-4-yl)methanamine >99.0%
250mg
$ 89.00

Chemenu
(2,2-difluoro-2H-1,3-benzodioxol-4-yl)methanamine 95%+
25g
$ 1650.00

Chemenu
(2,2-difluoro-2H-1,3-benzodioxol-4-yl)methanamine 95%+
10g
$ 825.00

Chemenu
(2,2-difluoro-2H-1,3-benzodioxol-4-yl)methanamine 95%+
5g
$ 495.00

Biosynth Carbosynth
4-Aminomethyl-?2,?2-?difluoro-?1,?3-?benzodioxole
2 g
$ 500.00

Total 20 raw suppliers

Chemical Property of 4-Aminomethyl-2,2-difluoro-1,3-benzodioxole

Chemical Property:

PSA：44.48000
LogP:2.16710
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:1.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:187.04448479
Heavy Atom Count:13
Complexity:201

Purity/Quality:

99%, ^*data from raw suppliers

2,2-Difluoro-1,3-benzodioxole-4-methanamine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C2C(=C1)OC(O2)(F)F)CN
Uses 2,2-Difluoro-1,3-benzodioxole-4-methanamine is used to prepare functionalized 2,2-Difluoro-1,3-benzodioxoles by reactions of 4-lithiated intermediate with carbon electrophiles and nitrogen nucelphiles.

Technology Process of 4-Aminomethyl-2,2-difluoro-1,3-benzodioxole

There total 8 articles about 4-Aminomethyl-2,2-difluoro-1,3-benzodioxole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%