Thieno(2',3':2,3)thiepino(4,5-c)pyridazin-3(2H)-one, 2-(4-chlorophenyl)-9-ethyl-5,6-dihydro-

Base Information

Chemical Name:Thieno(2',3':2,3)thiepino(4,5-c)pyridazin-3(2H)-one, 2-(4-chlorophenyl)-9-ethyl-5,6-dihydro-
CAS No.:135279-23-1
Molecular Formula:C18H15ClN2OS2
Molecular Weight:374.9075
Hs Code.:
DSSTox Substance ID:DTXSID10159295

Synonyms:2-(4-Chlorophenyl)-9-ethyl-5,6-dihydrothieno(2',3':2,3)thiepino(4,5-c)pyridazin-3(2H)-one;Thieno(2',3':2,3)thiepino(4,5-c)pyridazin-3(2H)-one, 2-(4-chlorophenyl)-9-ethyl-5,6-dihydro-;135279-23-1;C18H15ClN2OS2;SCHEMBL7289101;DTXSID10159295;C18-H15-Cl-N2-O-S2;LS-152560

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Thieno(2',3':2,3)thiepino(4,5-c)pyridazin-3(2H)-one, 2-(4-chlorophenyl)-9-ethyl-5,6-dihydro-

Chemical Property:

Boiling Point:556.2°Cat760mmHg
Flash Point:290.2°C
Density:1.45g/cm³
XLogP3:5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:374.0314331
Heavy Atom Count:24
Complexity:571

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1=CC2=C(S1)SCCC3=CC(=O)N(N=C32)C4=CC=C(C=C4)Cl

Technology Process of Thieno(2',3':2,3)thiepino(4,5-c)pyridazin-3(2H)-one, 2-(4-chlorophenyl)-9-ethyl-5,6-dihydro-

There total 6 articles about Thieno(2',3':2,3)thiepino(4,5-c)pyridazin-3(2H)-one, 2-(4-chlorophenyl)-9-ethyl-5,6-dihydro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 135279-22-0
2-(4-chlorophenyl)-9-ethyl-4,4a,5,6-tetrahydrothieno[2',3':2,3]thiepino[4,5-c]-pyridazin-3(2H)-one

: 135279-23-1
2-(4-chlorophenyl)-9-ethyl-5,6-dihydrothieno[2',3':2,3]-thiepino[4,5-c]pyridazin-3(2H)-one

Guidance literature:: With hydrogen bromide; In acetic acid; dimethyl sulfoxide; for 0.5h; Ambient temperature;
DOI:10.1016/0223-5234(96)88305-X

Reference yield:

: 135279-12-8
(2-Ethyl-4-oxo-4,5,6,7-tetrahydro-thieno[2,3-b]thiepin-5-yl)-acetonitrile

: 135279-23-1
2-(4-chlorophenyl)-9-ethyl-5,6-dihydrothieno[2',3':2,3]-thiepino[4,5-c]pyridazin-3(2H)-one

Guidance literature:: Multi-step reaction with 4 steps

1: conc. HCl, acetic acid / 4 h / Heating

2: sodium acetate / ethanol / 15 h / Heating

3: sodium acetate / acetic acid / 3 h / Heating

4: 80 percent / HBr / dimethylsulfoxide; acetic acid / 0.5 h / Ambient temperature

With hydrogenchloride; hydrogen bromide; sodium acetate; acetic acid; In ethanol; acetic acid; dimethyl sulfoxide;
DOI:10.1016/0223-5234(96)88305-X

Reference yield:

: 135278-99-8
2-ethyl-4-oxo-4,5,6,7-tetrahydrothieno[2,3-b]thiepin-5-acetic acid

: 135279-23-1
2-(4-chlorophenyl)-9-ethyl-5,6-dihydrothieno[2',3':2,3]-thiepino[4,5-c]pyridazin-3(2H)-one

Guidance literature:: Multi-step reaction with 3 steps

1: sodium acetate / ethanol / 15 h / Heating

2: sodium acetate / acetic acid / 3 h / Heating

3: 80 percent / HBr / dimethylsulfoxide; acetic acid / 0.5 h / Ambient temperature

With hydrogen bromide; sodium acetate; In ethanol; acetic acid; dimethyl sulfoxide;
DOI:10.1016/0223-5234(96)88305-X