3α,5α-Tetrahydronorethisterone

Base Information

• Chemical Name: 3α,5α-Tetrahydronorethisterone
• CAS No.: 16392-60-2
• Molecular Formula: C₂₀H₃₀O₂
• Molecular Weight: 302.457
• Mol file: 16392-60-2.mol

Synonyms:Tetrahydronorethisterone;(3α,5α,17α)-19-Norpregn-20-yne-3,17-diol;17α-Ethynyl-5α-oestrane-3α,17β-diol;19-Nor-5α,17α-pregn-20-yne-3α,17-diol;17α-Ethynyl-5α-estrane-3α,17β-diol-d5;17α-Ethynyl-5α-oestrane-3α,17β-diol-d5;19-Nor-5α,17α-pregn-20-yne-3α,17-diol-d5

Chemical Property of 3α,5α-Tetrahydronorethisterone

Chemical Property:

• Melting Point: 117-119 °C
• Boiling Point: 428.9±18.0 °C(Predicted)
• PKA: 13.11±0.60(Predicted)
• PSA: 40.46000
• Density: 1.13±0.1 g/cm3(Predicted)
• LogP: 3.36420
• Storage Temp.: Refrigerator
• Solubility.: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

98% ^*data from raw suppliers

3α,5α-Tetrahydronorethisterone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: A 3α-metabolite of progesterone receptor agonist Norethindrone (N676000) that acts as a estrogen receptor in osteoblastic cells. It also has novel nongenomic endothelium-independent vasorelaxing effec ts. A 3α-metabolite of progesterone receptor agonist Norethindrone (N676000) that acts as an estrogen receptor in osteoblastic cells. It also has novel nongenomic endothelium-independent vaso-relaxing effects.

Technology Process of 3α,5α-Tetrahydronorethisterone

There total 2 articles about 3α,5α-Tetrahydronorethisterone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 17α-Aethinyl-19-norandrostan-3β,17β-diol (1093-46-5,6424-05-1,16392-60-2,25796-09-2,77059-20-2)

Guidance literature:

17α-Aethinyl-19-norandrostan-17β-ol-3-on, NaBH4;

Reference yield:

→ 17α-Ethinyl-19-nor-androstan-3β,17β-diol (1093-46-5,6424-05-1,16392-60-2,25796-09-2,77059-20-2)

Guidance literature:

17α-Ethinyl-17β-hydroxy-19-nor-androstan-3-on, Dioxan, NaBH4;