3alpha,5alpha-Tetrahydronorethisterone

Base Information

Chemical Name:3alpha,5alpha-Tetrahydronorethisterone
CAS No.:16392-60-2
Molecular Formula:C₂₀H₃₀O₂
Molecular Weight:302.457
Hs Code.:
UNII:7YHT3131XK
ChEMBL ID:CHEMBL3273988
DSSTox Substance ID:DTXSID30558120
Nikkaji Number:J357.911E
Wikidata:Q27269027
Mol file:16392-60-2.mol

Synonyms:3alpha,5alpha-Tetrahydronorethisterone;16392-60-2;7YHT3131XK;UNII-7YHT3131XK;3alpha,5alpha-Tetrahydronorethindrone;(3R,5S,8R,9R,10S,13S,14S,17R)-17-ethynyl-13-methyl-2,3,4,5,6,7,8,9,10,11,12,14,15,16-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol;17alpha-Ethynyl-5alpha-estrane-3alpha,17beta-diol;17alpha-Ethynyl-5alpha-oestrane-3alpha,17beta-diol;19-Nor-5alpha,17alpha-pregn-20-yne-3alpha,17-diol;19-Norpregn-20-yne-3,17-diol, (3alpha,5alpha,17beta)-;17.alpha.-Ethynyl-5.alpha.-estrane-3.alpha.,17.beta.-diol;CHEMBL3273988;DTXSID30558120;3.ALPHA.,5.ALPHA.-TETRAHYDRONORETHINDRONE;3.ALPHA.,5.ALPHA.-TETRAHYDRONORETHISTERONE;Q27269027;(3alpha,5alpha,17alpha)-19-Norpregn-20-yne-3,17-diol;17.ALPHA.-ETHYNYL-5.ALPHA.-OESTRANE-3.ALPHA.,17.BETA.-DIOL;19-NOR-5.ALPHA.,17.ALPHA.-PREGN-20-YNE-3.ALPHA.,17-DIOL;19-NORPREGN-20-YNE-3,17-DIOL, (3.ALPHA.,5.ALPHA.,17.BETA.)-

Suppliers and Price of 3alpha,5alpha-Tetrahydronorethisterone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3α,5α-Tetrahydronorethisterone
25mg
$ 1190.00

Medical Isotopes, Inc.
3α,5α-Tetrahydronorethisterone
2.5 mg
$ 650.00

Total 7 raw suppliers

Chemical Property of 3alpha,5alpha-Tetrahydronorethisterone

Chemical Property:

Melting Point:117-119 °C
Boiling Point:428.9±18.0 °C(Predicted)
PKA:13.11±0.60(Predicted)
PSA：40.46000
Density:1.13±0.1 g/cm3(Predicted)
LogP:3.36420
Storage Temp.:Refrigerator
Solubility.:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
XLogP3:3.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:302.224580195
Heavy Atom Count:22
Complexity:505

Purity/Quality:

≥95% ^*data from raw suppliers

3α,5α-Tetrahydronorethisterone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC12CCC3C4CCC(CC4CCC3C1CCC2(C#C)O)O
Isomeric SMILES:C[C@]12CC[C@@H]3[C@H]4CC[C@H](C[C@@H]4CC[C@H]3[C@@H]1CC[C@]2(C#C)O)O
Uses A 3α-metabolite of progesterone receptor agonist Norethindrone (N676000) that acts as a estrogen receptor in osteoblastic cells. It also has novel nongenomic endothelium-independent vasorelaxing effec ts. A 3α-metabolite of progesterone receptor agonist Norethindrone (N676000) that acts as an estrogen receptor in osteoblastic cells. It also has novel nongenomic endothelium-independent vaso-relaxing effects.

Technology Process of 3alpha,5alpha-Tetrahydronorethisterone

There total 2 articles about 3alpha,5alpha-Tetrahydronorethisterone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: