(4aR)-4a,5,6,7,8,8a-Hexahydro-4aα-hydroxy-6α-isopropenyl-4,8aα-dimethylnaphthalene-2(1H)-one

Base Information

Chemical Name:(4aR)-4a,5,6,7,8,8a-Hexahydro-4aα-hydroxy-6α-isopropenyl-4,8aα-dimethylnaphthalene-2(1H)-one
CAS No.:24405-57-0
Molecular Formula:C15H22O2
Molecular Weight:234.33
Hs Code.:

Synonyms:(4aR)-4a,5,6,7,8,8a-Hexahydro-4aα-hydroxy-4,8aα-dimethyl-6α-(1-methylvinyl)naphthalen-2(1H)-one;(4aR)-4a,5,6,7,8,8a-Hexahydro-4aα-hydroxy-6α-isopropenyl-4,8aα-dimethylnaphthalene-2(1H)-one;β-Rotunol;beta-Rotunol

Suppliers and Price of (4aR)-4a,5,6,7,8,8a-Hexahydro-4aα-hydroxy-6α-isopropenyl-4,8aα-dimethylnaphthalene-2(1H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
β-Rotunol 95+%
5mg
$ 810.00

Arctom
beta-Rotunol
5mg
$ 316.00

Total 12 raw suppliers

Chemical Property of (4aR)-4a,5,6,7,8,8a-Hexahydro-4aα-hydroxy-6α-isopropenyl-4,8aα-dimethylnaphthalene-2(1H)-one

Chemical Property:

Melting Point:118-119℃
Boiling Point:351.4±42.0 °C(Predicted)
PKA:13.40±0.70(Predicted)
PSA：37.30000
Density:1.073±0.06 g/cm3(Predicted)
LogP:3.01910

Purity/Quality:

99%, ^*data from raw suppliers

β-Rotunol 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (4aR)-4a,5,6,7,8,8a-Hexahydro-4aα-hydroxy-6α-isopropenyl-4,8aα-dimethylnaphthalene-2(1H)-one

There total 15 articles about (4aR)-4a,5,6,7,8,8a-Hexahydro-4aα-hydroxy-6α-isopropenyl-4,8aα-dimethylnaphthalene-2(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 68974-90-3
eudesma-3,11-dien-2α,5β-diol

: 24405-57-0
β-rotunol

Guidance literature:: With manganese(IV) oxide; In dichloromethane; for 16h; Ambient temperature;
DOI:10.1246/bcsj.55.1195

Reference yield: 85.0%

: 68962-03-8
eudesma-3,11-dien-2β,5β-diol

: 24405-57-0
β-rotunol

Guidance literature:: With manganese(IV) oxide; In dichloromethane; for 16h; Ambient temperature;
DOI:10.1246/bcsj.55.1195

Reference yield:

: 68961-96-6
2β-(t-butyldimethylsilyloxy)eudesma-4,11-dien-3β-ol

: 24405-57-0
β-rotunol

Guidance literature:: Multi-step reaction with 5 steps

1: 1.0 g / VO(acac)2, t-butyl hydroperoxide / benzene / 0.17 h / Heating

2: 292 mg / pyridine / 2 h / Ambient temperature

3: 95 percent / liq. NH₃, Na / tetrahydrofuran / 0.08 h / -50 °C

4: 90 percent / acetic acid, water / tetrahydrofuran / 16 h / Ambient temperature

5: 85 percent / mangnanese(IV) oxide / CH₂Cl₂ / 16 h / Ambient temperature

With pyridine; tert.-butylhydroperoxide; manganese(IV) oxide; bis(acetylacetonate)oxovanadium; ammonia; water; sodium; acetic acid; In tetrahydrofuran; dichloromethane; benzene;
DOI:10.1246/bcsj.55.1195