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Technology Process of Articaine hydrochloride

Articaine hydrochloride

Base Information
  • Chemical Name:Articaine hydrochloride
  • CAS No.:23964-57-0
  • Molecular Formula:C13H20N2O3S.HCl
  • Molecular Weight:320.84
  • Hs Code.:2934.90
  • European Community (EC) Number:245-957-7
  • UNII:QS9014Q792
  • DSSTox Substance ID:DTXSID2045444
  • Wikidata:Q27287472
  • NCI Thesaurus Code:C47404
  • RXCUI:2117
  • ChEMBL ID:CHEMBL1200819
  • Mol file:23964-57-0.mol
Articaine hydrochloride

Synonyms:Articain;Articaine;Carticain;Carticaine;Carticaine Hydrochloride;Hoe 045;Hoe 40045;Hoe-045;Hoe-40045;Hoe045;Hoe40045;Hydrochloride, Carticaine;Ultracaine

Suppliers and Price of Articaine hydrochloride
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • Articaine hydrochloride
  • 50mg
  • $ 80.00
  • Sigma-Aldrich
  • Articaine hydrochloride ≥98% (HPLC)
  • 50mg
  • $ 101.00
  • Sigma-Aldrich
  • Articaine hydrochloride European Pharmacopoeia (EP) Reference Standard
  • $ 190.00
  • Sigma-Aldrich
  • Articaine hydrochloride European Pharmacopoeia (EP) Reference Standard
  • y0000079
  • $ 190.00
  • Sigma-Aldrich
  • Articaine Hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material
  • 500mg
  • $ 129.00
  • Sigma-Aldrich
  • Articaine hydrochloride United States Pharmacopeia (USP) Reference Standard
  • 125mg
  • $ 366.00
  • Matrix Scientific
  • Methyl 4-methyl-3-[(N-propylalanyl)amino]-2-thiophenecarboxylate hydrochloride
  • 1g
  • $ 306.00
  • Matrix Scientific
  • Methyl 4-methyl-3-[(N-propylalanyl)amino]-2-thiophenecarboxylate hydrochloride
  • 500mg
  • $ 199.00
  • DC Chemicals
  • ArticaineHCl >99%
  • 1 g
  • $ 600.00
  • DC Chemicals
  • ArticaineHCl >99%
  • 250 mg
  • $ 400.00
Total 162 raw suppliers
Chemical Property of Articaine hydrochloride
Chemical Property:
  • Appearance/Colour:white powder 
  • Vapor Pressure:5.79E-08mmHg at 25°C 
  • Melting Point:177-178° 
  • Boiling Point:440.6 °C at 760 mmHg 
  • Flash Point:220.3 °C 
  • PSA：95.67000 
  • Density:1.178 g/cm3 
  • LogP:3.43560 
  • Storage Temp.:2-8°C 
  • Solubility.:H2O: soluble20mg/mL, clear 
  • Hydrogen Bond Donor Count:3
  • Hydrogen Bond Acceptor Count:5
  • Rotatable Bond Count:7
  • Exact Mass:320.0961414
  • Heavy Atom Count:20
  • Complexity:325
Purity/Quality:

99% *data from raw suppliers

Articaine hydrochloride *data from reagent suppliers

Safty Information:
  • Pictogram(s): Xi 
  • Hazard Codes:Xi 
  • Statements: 36/37/38 
  • Safety Statements: 26 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:CCCNC(C)C(=O)NC1=C(SC=C1C)C(=O)OC.Cl
  • Recent ClinicalTrials:The Effect of Buccal Infiltration Administration of Clonidine on the Success Rate of Inferior Alveolar Nerve Block
  • Recent EU Clinical Trials:Multicenter, randomized, split-mouth study to evaluate the acceptance and preference of lidocaine gel compared to injection anesthesia after non surgical periodontal treatment
  • Recent NIPH Clinical Trials:Phase III trial of articaine hydrochloride with adrenaline bitartrate
  • Description Articaine hydrochloride is a thiophene-containing local anesthetic pharmacologically similar to mepivacaine. Most local anesthetics act by abolishing voltage-gated sodium channel currents indiscriminately in all populations of neurons. Articaine is an amide local anesthetic most commonly used in dentistry. It possesses a unique ester side chain that is metabolized rapidly by circulating esterases. Articaine is reported to modify cardiac action potentials and ion currents only at concentrations higher than the therapeutic range needed to inhibit voltage-gated sodium channels.
  • Uses Articaine hydrochloride is the hydrochloride Salt of Articaine, a amide based short-acting local anesthetic use for regional anaesthesia in day-case settings such arthroscopy, hand , food surgery and in dentistry.
  • Therapeutic Function Local anesthetic
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