(4-chloro-2-fluoro-phenyl)-carbaMic acid tert-butyl ester

Base Information

Chemical Name:(4-chloro-2-fluoro-phenyl)-carbaMic acid tert-butyl ester
CAS No.:956828-47-0
Molecular Formula:C11H13ClFNO2
Molecular Weight:245.681
Hs Code.:
Mol file:956828-47-0.mol

Synonyms:(4-chloro-2-fluoro-phenyl)-carbaMic acid tert-butyl ester;tert-Butyl (4-chloro-2-fluorophenyl)carbaMate

Suppliers and Price of (4-chloro-2-fluoro-phenyl)-carbaMic acid tert-butyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Ambeed
tert-Butyl(4-chloro-2-fluorophenyl)carbamate 97%
5g
$ 91.00

Ambeed
tert-Butyl(4-chloro-2-fluorophenyl)carbamate 97%
1g
$ 30.00

Ambeed
tert-Butyl(4-chloro-2-fluorophenyl)carbamate 97%
250mg
$ 12.00

Alichem
tert-Butyl(4-chloro-2-fluorophenyl)carbamate
25g
$ 1060.50

Alichem
tert-Butyl(4-chloro-2-fluorophenyl)carbamate
10g
$ 495.00

Alichem
tert-Butyl(4-chloro-2-fluorophenyl)carbamate
5g
$ 300.00

AK Scientific
Tert-Butyl(4-chloro-2-fluorophenyl)carbamate
1g
$ 100.00

Total 15 raw suppliers

Chemical Property of (4-chloro-2-fluoro-phenyl)-carbaMic acid tert-butyl ester

Chemical Property:

Boiling Point:255.4±30.0 °C(Predicted)
PKA:11.90±0.70(Predicted)
PSA：38.33000
Density:1.262±0.06 g/cm3(Predicted)
LogP:3.89910
Storage Temp.:Sealed in dry,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

tert-Butyl(4-chloro-2-fluorophenyl)carbamate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (4-chloro-2-fluoro-phenyl)-carbaMic acid tert-butyl ester

There total 2 articles about (4-chloro-2-fluoro-phenyl)-carbaMic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 57946-56-2
2-fluoro-4-chloroaniline

: 956828-47-0
tert-butyl (4-chloro-2-fluorophenyl)carbamate

Guidance literature:: In 1,4-dioxane; for 48h; Reflux;

Reference yield: 48.9%

: 24424-99-5
di-tert-butyl dicarbonate

: 956828-47-0
tert-butyl (4-chloro-2-fluorophenyl)carbamate

Guidance literature:: 2-fluoro-4-chloroaniline; With lithium hexamethyldisilazane; In tetrahydrofuran; at 0 - 20 ℃; for 1.5h;

di-tert-butyl dicarbonate; In tetrahydrofuran; at 20 ℃; for 0.75h;

Reference yield: 56.0%

: 956828-47-0
tert-butyl (4-chloro-2-fluorophenyl)carbamate

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: tert-butyl (4-chloro-2-fluoro-6-formylphenyl)carbamate

Guidance literature:: tert-butyl (4-chloro-2-fluorophenyl)carbamate; With tert.-butyl lithium; In diethyl ether; pentane; at -40 ℃; for 2.16h; Inert atmosphere;

N,N-dimethyl-formamide; In diethyl ether; pentane; at -40 ℃; for 0.166667h; Inert atmosphere;