1-(4-Methoxybenzyl)-1H-pyrazole-4-carboxylic acid

Base Information

Chemical Name:1-(4-Methoxybenzyl)-1H-pyrazole-4-carboxylic acid
CAS No.:1105039-93-7
Molecular Formula:C12H12N2O3
Molecular Weight:232.239
Hs Code.:2933199090
European Community (EC) Number:866-162-7

Synonyms:1-(4-Methoxybenzyl)-1H-pyrazole-4-carboxylic acid;1105039-93-7;1-[(4-methoxyphenyl)methyl]pyrazole-4-carboxylic acid;1-(4-Methoxy-benzyl)-1H-pyrazole-4-carboxylic acid;1-[(4-methoxyphenyl)methyl]-1H-pyrazole-4-carboxylic acid;SCHEMBL369349;JMWJJDKQQMMJRG-UHFFFAOYSA-N;MFCD08456928;AKOS009585478;DS-10017;CS-0150392;EN300-73681;C71359;1-(4-methoxybenzyl)-1H-pyrazole-4-carboxylicacid;Z431977958

Suppliers and Price of 1-(4-Methoxybenzyl)-1H-pyrazole-4-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-(4-Methoxybenzyl)-1H-pyrazole-4-carboxylicAcid
50mg
$ 155.00

TRC
1-(4-Methoxybenzyl)-1H-pyrazole-4-carboxylicAcid
10mg
$ 45.00

SynQuest Laboratories
1-(4-Methoxybenzyl)-1H-pyrazole-4-carboxylic acid 97%
250 mg
$ 109.00

Crysdot
1-(4-Methoxybenzyl)-1H-pyrazole-4-carboxylicacid 95+%
1g
$ 297.00

Crysdot
1-(4-Methoxybenzyl)-1H-pyrazole-4-carboxylicacid 95+%
5g
$ 891.00

Chemenu
1-(4-Methoxybenzyl)-1H-pyrazole-4-carboxylicacid 95%
1g
$ 281.00

Chemenu
1-(4-Methoxybenzyl)-1H-pyrazole-4-carboxylicacid 95%
5g
$ 842.00

Apolloscientific
1-(4-Methoxybenzyl)-1H-pyrazole-4-carboxylic acid
250mg
$ 92.00

Ambeed
1-(4-Methoxybenzyl)-1H-pyrazole-4-carboxylicacid 97%
1g
$ 42.00

Ambeed
1-(4-Methoxybenzyl)-1H-pyrazole-4-carboxylicacid 97%
250mg
$ 18.00

Total 10 raw suppliers

Chemical Property of 1-(4-Methoxybenzyl)-1H-pyrazole-4-carboxylic acid

Chemical Property:

PSA：64.35000
LogP:1.63820
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:232.08479225
Heavy Atom Count:17
Complexity:265

Purity/Quality:

98% ^*data from raw suppliers

1-(4-Methoxybenzyl)-1H-pyrazole-4-carboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)CN2C=C(C=N2)C(=O)O

Technology Process of 1-(4-Methoxybenzyl)-1H-pyrazole-4-carboxylic acid

There total 5 articles about 1-(4-Methoxybenzyl)-1H-pyrazole-4-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 1448317-15-4
1-(4-methoxybenzyl)-1H-pyrazole-4-carbonitrile

: 1105039-93-7
1-(4-methoxybenzyl)-1H-pyrazole-4-carboxylic acid

Guidance literature:: With sodium hydroxide; In water; at 110 ℃;
DOI:10.1002/jlcr.3319

Reference yield:

: 37622-90-5
4-ethoxycarbonylpyrazole

: 2746-25-0
p-Methoxybenzyl bromide

: 1105039-93-7
1-(4-methoxybenzyl)-1H-pyrazole-4-carboxylic acid

Guidance literature:: 4-ethoxycarbonylpyrazole; p-Methoxybenzyl bromide; With potassium carbonate; In acetone; at 50 ℃; for 3h;

With ethanol; potassium hydroxide; at 65 ℃; for 6h;

Reference yield:

: 824-94-2
p-methoxybenzyl chloride

: 1105039-93-7
1-(4-methoxybenzyl)-1H-pyrazole-4-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: acetonitrile / 4 h / 20 °C / Reflux

2.1: lithium hydroxide / water; tetrahydrofuran; methanol / 20 - 60 °C

2.2: pH 1 - 2

With lithium hydroxide; In tetrahydrofuran; methanol; water; acetonitrile;