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Technology Process of Molidustat(BAY 85-3934)

Molidustat(BAY 85-3934)

Base Information
  • Chemical Name:Molidustat(BAY 85-3934)
  • CAS No.:1154028-82-6
  • Molecular Formula:C13H14N8O2
  • Molecular Weight:314.3
  • Hs Code.:
  • Mol file:1154028-82-6.mol
Molidustat(BAY 85-3934)

Synonyms:Molidustat(BAY 85-3934);BAY 85-3934;2-[6-(4-Morpholinyl)-4-pyrimidinyl]-4-(1H-1,2,3-triazol-1-yl)-1,2-dihydro-3H-pyrazol-3-one;2-[6-(Morpholin-4-yl)pyrimidin-4-yl]-4-(1H-1,2,3-triazol-1-yl)-1,2-dihydro-3H-pyrazol-3-one;Somatoprim

Suppliers and Price of Molidustat(BAY 85-3934)
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • DC Chemicals
  • Molidustat(BAY85-3934) >98%
  • 250 mg
  • $ 750.00
  • DC Chemicals
  • Molidustat(BAY85-3934) >98%
  • 100 mg
  • $ 450.00
  • Crysdot
  • Molidustat 98+%
  • 100mg
  • $ 435.00
  • Crysdot
  • Molidustat 98+%
  • 50mg
  • $ 270.00
  • Crysdot
  • Molidustat 98+%
  • 25mg
  • $ 165.00
  • Crysdot
  • Molidustat 98+%
  • 10mg
  • $ 90.00
  • Crysdot
  • Molidustat 98+%
  • 5mg
  • $ 60.00
  • ChemScene
  • Molidustat 99.26%
  • 100mg
  • $ 550.00
  • ChemScene
  • Molidustat 99.26%
  • 5mg
  • $ 120.00
  • ChemScene
  • Molidustat 99.26%
  • 10mg
  • $ 180.00
Total 65 raw suppliers
Chemical Property of Molidustat(BAY 85-3934)
Chemical Property:
  • Boiling Point:589.2±60.0 °C(Predicted) 
  • PKA:5.38±0.37(Predicted) 
  • PSA：106.75000 
  • Density:1.67±0.1 g/cm3(Predicted) 
  • LogP:-0.56210 
  • Solubility.:insoluble in EtOH; insoluble in H2O; ≥5.68 mg/mL in DMF 
Purity/Quality:

99%, *data from raw suppliers

Molidustat(BAY85-3934) >98% *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Description Hypoxia-inducible factor (HIF) is the major transcription factor involved in erythropoietin gene expression. Because oxygen-dependent degradation of the α subunit of HIF suppresses erythropoietin expression, stimulation of erythropoiesis by agents that prevent degradation of HIF has been one strategy for managing anemia. BAY 85-3934 stabilizes HIF from degradation in the proteasome by inhibiting HIF-1α prolyl hydroxylase (IC50 = 0.49 μM). Inhibition of HIF prolyl hydroxylase by BAY 85-3934 has been shown to increase endogenous production of erythropoietin. Molidustat(BAY 85-3934) has been investigated in clinical trial for treatment of patients with anemia associated with chronic kidney disease and/or end-stage renal disease.
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