3,5-Dimethylbenzoic acid (3,5-dimethylphenyl)methyl ester

Base Information

• Chemical Name: 3,5-Dimethylbenzoic acid (3,5-dimethylphenyl)methyl ester
• CAS No.: 55000-47-0
• Molecular Formula: C18H20O2
• Molecular Weight: 268.356
• Mol file: 55000-47-0.mol

Synonyms:3,5-Dimethylbenzoic acid (3,5-dimethylphenyl)methyl ester

Chemical Property of 3,5-Dimethylbenzoic acid (3,5-dimethylphenyl)methyl ester

Chemical Property:

• PSA: 26.30000
• LogP: 4.27720

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3,5-Dimethylbenzoic acid (3,5-dimethylphenyl)methyl ester

There total 3 articles about 3,5-Dimethylbenzoic acid (3,5-dimethylphenyl)methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

3,5-dimethylbenzaldehyde (5779-95-3) → 3,5-dimethylbenzyl 3,5-dimethylbenzoate (55000-47-0)

Guidance literature:

With bis(1,5-cyclooctadiene)nickel⁽⁰⁾; 1,3-bis-(2,6-diisopropylphenyl)-4,5-dichloroimidazol-2-ylidene; In toluene; at 23 - 60 ℃; Inert atmosphere;

DOI:10.1039/b926866a

Reference yield: 96.0%

1,3,5-trimethyl-benzene (108-67-8) → 3,5-dimethylbenzyl 3,5-dimethylbenzoate (55000-47-0)

Guidance literature:

With tert.-butylhydroperoxide; tetra-(n-butyl)ammonium iodide; In water; at 80 ℃; for 6h;

DOI:10.1039/c3cc40832a

Reference yield:

3,5-dimethylbenzyl alcohol (27129-87-9) → 3,5-dimethylbenzyl 3,5-dimethylbenzoate (55000-47-0)

Guidance literature:

With (bis[(2-diisopropylphosphino)ethyl]amine)Mn(CO)₂; at 150 ℃; for 24h; Catalytic behavior; Inert atmosphere;

DOI:10.1021/acscatal.6b03554

upstream raw materials:

3,5-dimethylbenzaldehyde

1,3,5-trimethyl-benzene

3,5-dimethylbenzyl alcohol

Refernces

• 1、 Doi, Ryohei,Kikushima, Kotaro,Ohashi, Masato,Ogoshi, Sensuke. "Synthesis, Characterization, and unique catalytic activities of a fluorinated nickel enolate". supporting information. p. 3276 - 3282. Retrieved 2015/03/30.
• 2、 Ogoshi, Sensuke,Hoshimoto, Yoichi,Ohashi, Masato. "Nickel-catalyzed Tishchenko reaction via hetero-nickelacycles by oxidative cyclization of aldehydes with nickel(0) complex". supporting information; experimental part. p. 3354 - 3356. Retrieved 2010/07/14.