4-aMino-5-nitrophthalodinitrile

Base Information

• Chemical Name: 4-aMino-5-nitrophthalodinitrile
• CAS No.: 79319-38-3
• Molecular Formula: C8H4N4O2
• Molecular Weight: 188.14296
• Mol file: 79319-38-3.mol

Synonyms:4-aMino-5-nitrophthalodinitrile

Chemical Property of 4-aMino-5-nitrophthalodinitrile

Chemical Property:

• PSA: 119.42000
• LogP: 2.02476

Purity/Quality:

99% ^*data from raw suppliers

4-Amino-5-nitrophthalonitrile ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 4-Amino-5-nitrophthalonitrile, can b used in the synthesis of various pharmaceutical and biologically active compounds. It is utilized in the synthesis of novel fully conjugated phenanthroline-appended phthalocyanine, which has been shown to be used for industrial manufacture of blue and green pigments.

Technology Process of 4-aMino-5-nitrophthalodinitrile

There total 5 articles about 4-aMino-5-nitrophthalodinitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

2-nitro-4,5-dibromoaniline (75293-97-9) + copper(II) cyanide (4367-08-2) → 5-amino-5-nitrophthalodinitrile (79319-38-3)

Guidance literature:

In nitrobenzene; N,N-dimethyl-formamide; at 187 - 188 ℃; for 4h;

Reference yield: 67.0%

4-bromo-5-nitrophthalonitrile (206268-72-6) → 5-amino-5-nitrophthalodinitrile (79319-38-3)

Guidance literature:

With ammonia; In N,N-dimethyl-formamide; at 55 ℃; for 10h;

Reference yield: 62.0%

zinc(II) cyanide (557-21-1) + 2-nitro-4,5-dibromoaniline (75293-97-9) → 5-amino-5-nitrophthalodinitrile (79319-38-3)

Guidance literature:

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; polymethylhydroxysilane; In N,N-dimethyl acetamide; at 120 ℃; for 6h;

DOI:10.1055/s-2008-1078269

upstream raw materials:

2-nitro-4,5-dibromoaniline

copper(II) cyanide

4-bromo-5-nitrophthalonitrile

copper(I) cyanide

Downstream raw materials:

5,6-dicyanobenzimidazole

5-nitro-4-(4-undecyloxybenzoylamino)phthalonitrile

4-benzoylamino-5-nitrophthalodinitrile

4,5-diaminophthalonitrile