Technology Process of 2-Nitro-6-(trifluoroMethoxy)benzenaMine
There total 3 articles about 2-Nitro-6-(trifluoroMethoxy)benzenaMine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogenchloride;
In
ethanol;
for 3.5h;
Heating;
DOI:10.1021/jm980202u
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 19 percent / nitronium tetrafluoroborate / acetonitrile / 0.5 h / -5 °C
2: 94 percent / conc. aq. HCl / ethanol / 3.5 h / Heating
With
hydrogenchloride; nitronium tetrafluoborate;
In
ethanol; acetonitrile;
DOI:10.1021/jm980202u
- Guidance literature:
-
1-nitro-3-(trifluoromethoxy)benzene;
With
N,N,N-trimethylhydrazinium iodide;
In
dimethyl sulfoxide;
at 0 ℃;
With
potassium tert-butylate;
In
water; dimethyl sulfoxide;
at 25 ℃;
for 4h;
With
hydrogenchloride; water;
In
dimethyl sulfoxide;
pH=2 - 3;