2-Benzyloxy-4-iodophenol

Base Information

Chemical Name:2-Benzyloxy-4-iodophenol
CAS No.:289471-92-7
Molecular Formula:C13H11IO2
Molecular Weight:326.134
Hs Code.:
DSSTox Substance ID:DTXSID00573002
Wikidata:Q82461554
Mol file:289471-92-7.mol

Synonyms:2-Benzyloxy-4-iodophenol;289471-92-7;2-(Benzyloxy)-4-iodophenol;4-iodo-2-phenylmethoxyphenol;4-Iodo-2-(phenylmethoxy)phenol;SCHEMBL17685895;DTXSID00573002;SUUAJTJMEHPEDV-UHFFFAOYSA-N;CS-0527518;G63100;A846303

Suppliers and Price of 2-Benzyloxy-4-iodophenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Benzyloxy-4-iodophenol
5g
$ 1540.00

TRC
2-Benzyloxy-4-iodophenol
500mg
$ 195.00

Crysdot
2-Benzyloxy-4-iodophenol 95+%
5g
$ 2300.00

Total 2 raw suppliers

Chemical Property of 2-Benzyloxy-4-iodophenol

Chemical Property:

PSA：29.46000
LogP:3.57580
XLogP3:3.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:325.98038
Heavy Atom Count:16
Complexity:204

Purity/Quality:

97% ^*data from raw suppliers

2-Benzyloxy-4-iodophenol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)COC2=C(C=CC(=C2)I)O
Uses 2-Benzyloxy-4-iodophenol is used in the preparation of isotope labelled Quercetin (Q509500) conjugates.

Technology Process of 2-Benzyloxy-4-iodophenol

There total 3 articles about 2-Benzyloxy-4-iodophenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.9%

: 6272-38-4
O-benzylcatechol

: 289471-92-7
2-(benzyloxy)-4-iodophenol

Guidance literature:: With sodium hypochlorite; sodium iodide; sodium hydroxide; In methanol; at -10 - 10 ℃; for 0.166667h;

Reference yield:

: 100-44-7
benzyl chloride

: 289471-92-7
2-(benzyloxy)-4-iodophenol

Guidance literature:: Multi-step reaction with 2 steps

1.1: NaOH / methanol / 0 - 3 °C

1.2: 32 percent / methanol / 2 h / Heating

2.1: NaI; NaOH / methanol

2.2: 35 percent / aq. NaClO / 1 h / 0 - 2 °C

With sodium hydroxide; sodium iodide; In methanol;
DOI:10.1021/ja0535357

Reference yield:

: 120-80-9,19481-10-8,37349-32-9
benzene-1,2-diol

: 289471-92-7
2-(benzyloxy)-4-iodophenol

Guidance literature:: Multi-step reaction with 2 steps

1.1: NaOH / methanol / 0 - 3 °C

1.2: 32 percent / methanol / 2 h / Heating

2.1: NaI; NaOH / methanol

2.2: 35 percent / aq. NaClO / 1 h / 0 - 2 °C

With sodium hydroxide; sodium iodide; In methanol;
DOI:10.1021/ja0535357