tert-butyl (3R,4R)-4-Methylpyrrolidin-3-ylcarbaMate

Base Information

• Chemical Name: tert-butyl (3R,4R)-4-Methylpyrrolidin-3-ylcarbaMate
• CAS No.: 127199-55-7
• Molecular Formula: C10H20N2O2
• Molecular Weight: 200.278
• Hs Code.: 2933990090
• Mol file: 127199-55-7.mol

Synonyms:tert-butyl (3R,4R)-4-Methylpyrrolidin-3-ylcarbaMate;(3R,4R)-3-(Boc-aMino)-4-Methylpyrrolidine;(3R,4R)-(4-Methyl-pyrrolidin-3-yl)-carbamic acid tert-butyl ester;(3R-cis)-(4-Methyl-3-pyrrolidinyl)carbamic acid 1,1-dimethylethyl ester

Chemical Property of tert-butyl (3R,4R)-4-Methylpyrrolidin-3-ylcarbaMate

Chemical Property:

• Boiling Point: 295.1±29.0 °C(Predicted)
• PKA: 12.39±0.40(Predicted)
• PSA: 50.36000
• Density: 1.02±0.1 g/cm3(Predicted)
• LogP: 1.83870

Purity/Quality:

97% ^*data from raw suppliers

(3R-cis)-(4-Methyl-3-pyrrolidinyl)-carbamicAcid1,1-DimethylethylEster ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: (3R-cis)-(4-Methyl-3-pyrrolidinyl)-carbamic Acid 1,1-Dimethylethyl Ester is used in the reaction and preparation of antibacterial agents.

Technology Process of tert-butyl (3R,4R)-4-Methylpyrrolidin-3-ylcarbaMate

There total 2 articles about tert-butyl (3R,4R)-4-Methylpyrrolidin-3-ylcarbaMate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

cis-1-phenylmethyl-3-(1,1-dimethylethoxycarbonylamino)-4-methylpyrrolidine → tert-butyl N-((3R,4R)-4-methylpyrrolidin-3-yl)carbamate (127199-55-7,1334481-84-3)

Guidance literature:

Pd(OH)2; In methanol;

Reference yield:

1-benzyl-3(S)-[(t-butoxycarbonyl)amino]-4(R)-methylpyrrolidine (174847-52-0) → tert-butyl N-((3R,4R)-4-methylpyrrolidin-3-yl)carbamate (127199-55-7,1334481-84-3)

Guidance literature:

palladium; In ethanol;

upstream raw materials:

1-benzyl-3(S)-[(t-butoxycarbonyl)amino]-4(R)-methylpyrrolidine