H-GLU-OTMSET

Base Information

Chemical Name:H-GLU-OTMSET
CAS No.:292045-49-9
Molecular Formula:C10H21NO4Si
Molecular Weight:247.36
Hs Code.:
Mol file:292045-49-9.mol

Synonyms:H-GLU-OTMSET;L-GLUTAMIC ACID ALPHA-2-TRIMETHYLSILYLETHYL ESTER;(S)-4-amino-5-oxo-5-(2-(trimethylsilyl)ethoxy)pentanoic acid

Suppliers and Price of H-GLU-OTMSET

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
H-GLU-OTMSET 95.00%
5MG
$ 503.61

Total 3 raw suppliers

Chemical Property of H-GLU-OTMSET

Chemical Property:

PSA：89.62000
LogP:1.76020

Purity/Quality:

95% ^*data from raw suppliers

H-GLU-OTMSET 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of H-GLU-OTMSET

There total 4 articles about H-GLU-OTMSET which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

: 160450-14-6
N-(tert-butoxycarbonyl)-α-[2-(trimethylsilyl)ethoxy]-L-glutamic acid

: 292045-49-9
α-[2-(trimethylsilyl)ethoxy]-L-glutamic acid

Guidance literature:: With toluene-4-sulfonic acid; In 1,4-dioxane; water; at 60 ℃; for 3h;
DOI:10.1021/jo000132a

Reference yield:

: 2916-68-9
2-(Trimethylsilyl)ethanol

: 292045-49-9
α-[2-(trimethylsilyl)ethoxy]-L-glutamic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 87 percent / CDI / CH₂Cl₂ / 18 h / 20 °C

2: 57 percent / TsOH-H₂O / H₂O; dioxane / 3 h / 60 °C

With toluene-4-sulfonic acid; 1,1'-carbonyldiimidazole; In 1,4-dioxane; dichloromethane; water; 1: Esterification / 2: Hydrolysis;
DOI:10.1021/jo000132a

Reference yield:

: 13574-13-5
Boc-Glu(OBzl)-OH

: 292045-49-9
α-[2-(trimethylsilyl)ethoxy]-L-glutamic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 87 percent / CDI / CH₂Cl₂ / 18 h / 20 °C

2: 57 percent / TsOH-H₂O / H₂O; dioxane / 3 h / 60 °C

With toluene-4-sulfonic acid; 1,1'-carbonyldiimidazole; In 1,4-dioxane; dichloromethane; water; 1: Esterification / 2: Hydrolysis;
DOI:10.1021/jo000132a