(2S,3S)-FMoc-Abu(3-N3)-OH

Base Information

• Chemical Name: (2S,3S)-FMoc-Abu(3-N3)-OH
• CAS No.: 131669-42-6
• Molecular Formula: C19H18N4O4
• Molecular Weight: 366.376
• Hs Code.: 9999999999
• Mol file: 131669-42-6.mol

Synonyms:(2S,3S)-FMoc-Abu(3-N3)-OH;Fmoc-Abu(3-N3)-OH (2S,3S);[S-(R*,R*)]-3-Azido-2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]butanoic acid

Chemical Property of (2S,3S)-FMoc-Abu(3-N3)-OH

Chemical Property:

• PSA: 125.38000
• LogP: 3.52076
• Storage Temp.: Store at -15°C to -25°C.

Purity/Quality:

97% ^*data from raw suppliers

Fmoc-Abu(3-N3)-OH(2S,3S) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Protected derivative for the synthesis of 2,3-diaminobutanoic acid containing peptides and also for click reactions.

Technology Process of (2S,3S)-FMoc-Abu(3-N3)-OH

There total 5 articles about (2S,3S)-FMoc-Abu(3-N3)-OH which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

(2S,3S)-3-azido-N'-(tert-butoxycarbonyl)-2-(fluorenylmethoxycarbonylamino)butyrohydrazide (146306-77-6) → (2S,3S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-azidobutanoic acid (131669-42-6)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; at 80 ℃; for 16h;

DOI:10.1055/s-1992-26332

Reference yield:

C4H8N4O2 + N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide (82911-69-1) → (2S,3S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-azidobutanoic acid (131669-42-6)

Guidance literature:

With sodium carbonate; In tetrahydrofuran; water; at 0 - 20 ℃; for 18h;

DOI:10.1002/cmdc.201700300

Reference yield:

(2S,3S)-3-azido-2-(fluoren-9-ylmethoxycarbonylamino)butyric acid methyl ester → (2S,3S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-azidobutanoic acid (131669-42-6)

Guidance literature:

With calcium chloride; lithium hydroxide; In tetrahydrofuran; water; isopropyl alcohol;

DOI:10.1002/anie.202009092

upstream raw materials:

(2S,3S)-3-azido-N'-(tert-butoxycarbonyl)-2-(fluorenylmethoxycarbonylamino)butyrohydrazide

(2S,3R)-N'-(tert-butoxycarbonyl)-2-(fluoren-9-ylmethoxycarbonylamino)-3-hydroxybutyrohydrazide

Fmoc-Thr-OH

N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 131669-42-6 (2S,3S)-FMoc-Abu(3-N3)-OH

Send

Send

Metric Ton KG G Pound L ML

Send

Send