1-(3-chlorophenyl)-2,2,2-trifluoroethanamine

Base Information

• Chemical Name: 1-(3-chlorophenyl)-2,2,2-trifluoroethanamine
• CAS No.: 886368-66-7
• Molecular Formula: C₈H₇ClF₃N
• Molecular Weight: 209.598
• Hs Code.: 2921490090
• Mol file: 886368-66-7.mol

Synonyms:1-(3-chlorophenyl)-2,2,2-trifluoroethanamine;1-(3-Chlorophenyl)-2,2,2-trifluoroethan-1-amine;2,2,2-Trifluoro-1-(3-chloro-phenyl)-ethylamine

Chemical Property of 1-(3-chlorophenyl)-2,2,2-trifluoroethanamine

Chemical Property:

• PSA: 26.02000
• LogP: 3.60240

Purity/Quality:

98%Min ^*data from raw suppliers

1-(3-Chlorophenyl)-2,2,2-trifluoroethylamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 1-(3-Chlorophenyl)-2,2,2-trifluoroethylamine

Technology Process of 1-(3-chlorophenyl)-2,2,2-trifluoroethanamine

There total 1 articles about 1-(3-chlorophenyl)-2,2,2-trifluoroethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ (rac)-1-(3-chlorophenyl)-2,2,2-trifluoroethanamine (886368-66-7,1212224-82-2)

Guidance literature:

With titanium tetrachloride; triethylamine; benzylamine; In diethyl ether; hexane; at 0 - 20 ℃; for 16h;

Reference yield: 39.0%

(rac)-1-(3-chlorophenyl)-2,2,2-trifluoroethanamine (886368-66-7,1212224-82-2) + 2-chloro-7-methoxy-1,3-benzoxazole-5-carboxylic acid methyl ester → methyl (rac)-methyl 2-{[1-(3-chlorophenyl)-2,2,2-trifluoroethyl]amino}-7-methoxy-1,3-benzoxazole-5-carboxylate

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at 20 ℃; for 18h; Inert atmosphere;

DOI:10.1021/acs.jmedchem.0c01035

Refernces