4-(isopropylamino)-5-(methoxycarbonyl)thiophen-2-ylboronic acid

Base Information

Chemical Name:4-(isopropylamino)-5-(methoxycarbonyl)thiophen-2-ylboronic acid
CAS No.:1027708-14-0
Molecular Formula:C₉H₁₄BNO₄S
Molecular Weight:243.091
Hs Code.:
Mol file:1027708-14-0.mol

Synonyms:4-(isopropylamino)-5-(methoxycarbonyl)thiophen-2-ylboronic acid

Suppliers and Price of 4-(isopropylamino)-5-(methoxycarbonyl)thiophen-2-ylboronic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-(isopropylamino)-5-(methoxycarbonyl)thiophen-2-ylboronic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4-(isopropylamino)-5-(methoxycarbonyl)thiophen-2-ylboronic acid

There total 4 articles about 4-(isopropylamino)-5-(methoxycarbonyl)thiophen-2-ylboronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: {4-[[(trans-4-methylcyclohexyl)carbonyl](1-methylethyl)amino]-5-[(methyloxy)carbonyl]-2-thienyl}boronic acid

: 1027708-14-0
{4-[(1-methylethyl)amino]-5-[(methyloxy)carbonyl]-2-thienyl}boronic acid

Guidance literature:: With trifluoroacetic acid; for 1.5h; Heating / reflux;

Reference yield:

: 22288-78-4
Methyl 3-aminothiophene-2-carboxylate

: 1027708-14-0
{4-[(1-methylethyl)amino]-5-[(methyloxy)carbonyl]-2-thienyl}boronic acid

Guidance literature:: Multi-step reaction with 4 steps

1.1: sodium tris(acetoxy)borohydride; acetic acid / dichloromethane / 25 °C

2.1: 1,2-dichloro-ethane / 21 °C / Heating / reflux

3.1: lithium diisopropyl amide / tetrahydrofuran; n-heptane; ethylbenzene / 1 h / -78 - -70 °C

3.2: 0.33 h / -70 °C

3.3: 21 °C

4.1: trifluoroacetic acid / 1.5 h / Heating / reflux

With sodium tris(acetoxy)borohydride; acetic acid; trifluoroacetic acid; lithium diisopropyl amide; In tetrahydrofuran; n-heptane; dichloromethane; ethylbenzene; 1,2-dichloro-ethane;

Reference yield:

: 3-isopropyl(trans-4-methylcyclohexylcarbonyl)amino-thiophene-2-carboxylic acid methyl ester

: 1027708-14-0
{4-[(1-methylethyl)amino]-5-[(methyloxy)carbonyl]-2-thienyl}boronic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: lithium diisopropyl amide / tetrahydrofuran; n-heptane; ethylbenzene / 1 h / -78 - -70 °C

1.2: 0.33 h / -70 °C

1.3: 21 °C

2.1: trifluoroacetic acid / 1.5 h / Heating / reflux

With trifluoroacetic acid; lithium diisopropyl amide; In tetrahydrofuran; n-heptane; ethylbenzene;