(S)-3-Fluoropiperidine hy...

Base Information

• Chemical Name: (S)-3-Fluoropiperidine hy...
• CAS No.: 871664-50-5
• Molecular Formula: C5H11ClFN
• Molecular Weight: 139.6
• Mol file: 871664-50-5.mol

Synonyms:(S)-3-Fluoropiperidine hy...;(S)-3-Fluoropiperidine hydrochloride;(3S)-3-fluoropiperidine hydrochloride;(S)-3-Fluoro-piperidine

Chemical Property of (S)-3-Fluoropiperidine hy...

Chemical Property:

• PSA: 12.03000
• LogP: 1.83870

Purity/Quality:

97% ^*data from raw suppliers

(S)-3-Fluoropiperidinehydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (S)-3-Fluoropiperidine hy...

There total 1 articles about (S)-3-Fluoropiperidine hy... which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tert-butyl (3S)-3-fluoropiperidine-1-carboxylate → (3S)-3-fluoropiperidine hydrochloride (871664-50-5)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; dichloromethane; at 20 ℃;

Reference yield: 77.0%

(3S)-3-fluoropiperidine hydrochloride (871664-50-5) + 2-(3-(1-(2-fluorophenyl)-1H-indazol-4-yl)-2-oxoimidazolidin-1-yl)acetic acid → 1-[1-(2-fluorophenyl)-1H-indazol-4-yl]-3-{2-[(3S)-3-fluoropiperidin-1-yl]-2-oxoethyl}imidazolidin-2-one

Guidance literature:

With HATU; In N,N-dimethyl-formamide; at 20 ℃; for 18h;