2-Bromo-6-(4-(trifluoromethyl)phenyl)pyridine

Base Information

Chemical Name:2-Bromo-6-(4-(trifluoromethyl)phenyl)pyridine
CAS No.:637352-38-6
Molecular Formula:C12H7BrF3N
Molecular Weight:302.09
Hs Code.:
DSSTox Substance ID:DTXSID40593885
Wikidata:Q82488516
Mol file:637352-38-6.mol

Synonyms:2-bromo-6-(4-(trifluoromethyl)phenyl)pyridine;637352-38-6;2-Bromo-6-[4-(trifluoromethyl)phenyl]pyridine;SCHEMBL5650095;DTXSID40593885;AKOS014984947;DB-313733;CS-0365323;2-bromo-6-[4-(trifluoromethyl) phenyl]pyridine;J-508422

Suppliers and Price of 2-Bromo-6-(4-(trifluoromethyl)phenyl)pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
2-Bromo-6-(4-(trifluoromethyl)phenyl)pyridine 95%
1g
$ 482.00

American Custom Chemicals Corporation
2-BROMO-6-(4-(TRIFLUOROMETHYL)PHENYL)PYRIDINE 95.00%
5MG
$ 501.58

Alichem
2-Bromo-6-(4-(trifluoromethyl)phenyl)pyridine
1g
$ 420.16

Total 11 raw suppliers

Chemical Property of 2-Bromo-6-(4-(trifluoromethyl)phenyl)pyridine

Chemical Property:

PSA：12.89000
LogP:4.52990
Storage Temp.:2-8°C
XLogP3:4.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:300.97140
Heavy Atom Count:17
Complexity:249

Purity/Quality:

≥95% ^*data from raw suppliers

2-Bromo-6-(4-(trifluoromethyl)phenyl)pyridine 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=NC(=C1)Br)C2=CC=C(C=C2)C(F)(F)F

Technology Process of 2-Bromo-6-(4-(trifluoromethyl)phenyl)pyridine

There total 4 articles about 2-Bromo-6-(4-(trifluoromethyl)phenyl)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

: 626-05-1
2,6-Dibromopyridine

: potassium 4-(trifluoromethyl)phenyltrifluoroborate

: 637352-38-6
2-bromo-6-[4-(trifIuoromethyl)phenyl]pyridine

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium chloride; sodium carbonate; triphenylphosphine; In ethanol; water; toluene; at 40 ℃; for 6h; Sealed tube;
DOI:10.1002/ejoc.201400090

Reference yield:

: 626-05-1
2,6-Dibromopyridine

: 128796-39-4
4-trifluoromethylphenylboronic acid

: 637352-38-6
2-bromo-6-[4-(trifIuoromethyl)phenyl]pyridine

Guidance literature:: With sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In DME (dimethoxyethane); for 5h; Heating / reflux;

Reference yield:

: 626-05-1
2,6-Dibromopyridine

: 718628-25-2
(4-(trifluoromethyl)phenyl)zinc(II) iodide

: 637352-38-6
2-bromo-6-[4-(trifIuoromethyl)phenyl]pyridine

: 581-80-6
4,4'-bis(trifluoromethyl)biphenyl

: 1160096-68-3
2,6-bis(4-(trifluoromethyl)phenyl)pyridine

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; In tetrahydrofuran; at 20 ℃; for 0.5h; Reagent/catalyst; Temperature; regioselective reaction; Inert atmosphere;
DOI:10.5012/bkcs.2014.35.1.280