8-Fluoro-4-hydrazinoquinoline

Base Information

Chemical Name:8-Fluoro-4-hydrazinoquinoline
CAS No.:49611-99-6
Molecular Formula:C9H8FN3
Molecular Weight:177.18
Hs Code.:2933990090
DSSTox Substance ID:DTXSID70534685
Wikidata:Q82408629
Mol file:49611-99-6.mol

Synonyms:8-Fluoro-4-hydrazinoquinoline;49611-99-6;8-Fluoro-4-hydrazineoquinoline;(8-fluoroquinolin-4-yl)hydrazine;8-Fluoro-4-hydrazinylquinoline;SCHEMBL15209925;DTXSID70534685;AKOS002683751;AB05761;CS-0530468

Suppliers and Price of 8-Fluoro-4-hydrazinoquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
8-FLUORO-4-HYDRAZINOQUINOLINE 95.00%
5MG
$ 503.35

Total 3 raw suppliers

Chemical Property of 8-Fluoro-4-hydrazinoquinoline

Chemical Property:

PSA：50.94000
LogP:2.43280
XLogP3:1.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:177.07022543
Heavy Atom Count:13
Complexity:176

Purity/Quality:

98%min ^*data from raw suppliers

8-FLUORO-4-HYDRAZINOQUINOLINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C=CN=C2C(=C1)F)NN

Technology Process of 8-Fluoro-4-hydrazinoquinoline

There total 2 articles about 8-Fluoro-4-hydrazinoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 63010-72-0
4-chloro-8-fluoro-quinoline

: 49611-99-6
8-fluoro-4-hydrazinylquinoline

Guidance literature:: With hydrazine hydrate; In ethanol; at 80 ℃; for 16h;

Reference yield:

: 148401-38-1
4-amino-8-fluoroquinoline

: 49611-99-6
8-fluoro-4-hydrazinylquinoline

Guidance literature:: Multi-step reaction with 2 steps

1.1: hydrogenchloride; sodium nitrite / water / 0.5 h / 0 °C

1.2: 2 h / 20 °C

2.1: hydrazine hydrate / ethanol / 1 h / 160 °C / Microwave irradiation

With hydrogenchloride; hydrazine hydrate; sodium nitrite; In ethanol; water;

Reference yield:

: 49611-99-6
8-fluoro-4-hydrazinylquinoline

: 1452182-61-4
4-tert-butyl-N-(1-(8-fluoroquinolin-4-yl)-3-methyl-1H-pyrazol-5-yl)benzenesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / ethanol / 15 h / 80 °C

2: pyridine / 15 h / 80 °C

With pyridine; In ethanol;